Where and when natriuretic peptides are secreted in the heart

被引:0
作者
I. M. Korostyshevskaya
V. F. Maksimov
机构
[1] Russian Academy of Medical Sciences,Institute of Physiology, Siberian Branch
来源
Russian Journal of Developmental Biology | 2012年 / 43卷
关键词
natriuretic peptides; water-salt homeostasis; embryogenesis; heart;
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摘要
This review presents recent data on the structure, synthesis, and secretion of cardiac natriuretic peptides. It is known that these hormones have a broad spectrum of activity, but they remain the least studied and poorly understood link in the regulation of the water-salt homeostasis. Emphasis is placed on the problem of ontogenetic formation of the heart secretory activity during embryogenesis. We discuss the available scarce and scattered information on the paracrine and autocrine effects of the peptides on intercellular interactions, and on the division, growth and differentiation of the heart cells. These issues are hardly addressed in Russian literature.
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页码:185 / 195
页数:10
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