Autism-associated CHD8 deficiency impairs axon development and migration of cortical neurons

被引：0
|
作者：
Qiong Xu
Yuan-yuan Liu
Xiaoming Wang
Guo-he Tan
Hui-ping Li
Samuel W. Hulbert
Chun-yang Li
Chun-chun Hu
Zhi-qi Xiong
Xiu Xu
Yong-hui Jiang
机构：
[1] Children’s Hospital of Fudan University,Department of Child Health Care
[2] Guangxi Medical University,Guangxi Key Laboratory of Regenerative Medicine & Guangxi Collaborative Innovation Center for Biomedicine, School of Preclinical Medicine
[3] Duke University School of Medicine,Department of Pediatrics
[4] Duke University School of Medicine,Department of Neurobiology
[5] Chinese Academy of Sciences,Institute of Neuroscience & State Key Laboratory of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, Shanghai Institutes for Biological Sciences
[6] University of Chinese Academy of Sciences,Program in Genetics and Genomics
[7] Duke University School of Medicine,Cellular Molecular Biology
[8] Duke University School of Medicine,undefined
来源：
Molecular Autism | / 9卷
关键词：
CHD8; Autism spectrum disorder (ASD); Chromatin remodeling; Neurite growth; Neurodevelopment;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 45 条
  • [41] Disruption of the autism-associated gene SCN2A alters synaptic development and neuronal signaling in patient iPSC-glutamatergic neurons
    Brown, Chad O.
    Uy, Jarryll A.
    Murtaza, Nadeem
    Rosa, Elyse
    Alfonso, Alexandria
    Dave, Biren M.
    Kilpatrick, Savannah
    Cheng, Annie A.
    White, Sean H.
    Scherer, Stephen W.
    Singh, Karun K.
    FRONTIERS IN CELLULAR NEUROSCIENCE, 2024, 17
  • [42] Modeling human telencephalic development and autism-associated SHANK3 deficiency using organoids generated from single neural rosettes
    Yueqi Wang
    Simone Chiola
    Guang Yang
    Chad Russell
    Celeste J. Armstrong
    Yuanyuan Wu
    Jay Spampanato
    Paisley Tarboton
    H. M. Arif Ullah
    Nicolas U. Edgar
    Amelia N. Chang
    David A. Harmin
    Vittoria Dickinson Bocchi
    Elena Vezzoli
    Dario Besusso
    Jun Cui
    Elena Cattaneo
    Jan Kubanek
    Aleksandr Shcheglovitov
    Nature Communications, 13
  • [43] Modeling human telencephalic development and autism-associated SHANK3 deficiency using organoids generated from single neural rosettes
    Wang, Yueqi
    Chiola, Simone
    Yang, Guang
    Russell, Chad
    Armstrong, Celeste J.
    Wu, Yuanyuan
    Spampanato, Jay
    Tarboton, Paisley
    Ullah, H. M. Arif
    Edgar, Nicolas U.
    Chang, Amelia N.
    Harmin, David A.
    Bocchi, Vittoria Dickinson
    Vezzoli, Elena
    Besusso, Dario
    Cui, Jun
    Cattaneo, Elena
    Kubanek, Jan
    Shcheglovitov, Aleksandr
    NATURE COMMUNICATIONS, 2022, 13 (01)
  • [44] CELF2 Deficiency Demonstrates Autism-Like Behaviors and Interferes with Late Development of Cortical Neurons in Mice
    Duan, Xinyu
    Peng, Xiaoxia
    Jia, Xiangbin
    Tan, Senwei
    Guo, Hui
    Tan, Jieqiong
    Hu, Zhangxue
    MOLECULAR NEUROBIOLOGY, 2025, 62 (01) : 156 - 168
  • [45] RNA-SEQ ANALYSIS OF HUMAN NEURONS DERIVED FROM INDUCED PLURIPOTENT STEM CELLS CONTAINING A KNOCKOUT OF THE AUTISM AND SCHIZOPHRENIA CANDIDATE GENE CHD8 (CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN)
    Wang, Ping
    Lin, Mingyan
    Pedrosa, Erika
    Hrabovsky, Anastasia
    Guo, Wenjun
    Zhang, Zheng
    Zheng, Deyou
    Lachman, Herb
    EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2017, 27 : S220 - S220
12345