A new naphtho-γ-pyrone from mangrove endophytic fungus ZSU-H26

被引：0
作者：
Zhongjing Huang
Ruiyun Yang
Zhiyong Guo
Zhigang She
Yongcheng Lin
机构：
[1] Guangxi University for Nationalities,College of Chemistry and Ecology Engineering
[2] Guangxi Normal University,College of Chemistry and Chemical Engineering
[3] China Three Gorges University,College of Chemistry and Life Science
[4] Sun Yat-Sen (Zhongshan) University,College of Chemistry and Chemical Engineering
来源：
Chemistry of Natural Compounds | 2010年 / 46卷
关键词：
mangrove endophytic fungus; naphtho-; -pyrone; metabolites;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A new naphtho-γ-pyrone, 5-hydroxy-6,8-dimethoxy-2-benzyl-4H-naphtho[2,3-b]-pyran-4-one (1), together with three known compounds 5,7-dihydroxy-2-methylbenzopyran-4-one (2), 3,5-dihydroxy-2,7dimethylbenzopyran-4-one (3) and cyclo(Tyr-Tyr) (4) were isolated from the mangrove endophytic fungus Phomopsis sp. ZSU-H26 obtained from the South China Sea. Their structures were elucidated by spectroscopic methods, mainly 1D and 2D NMR spectroscopic techniques. Primary bioassays showed that 1 exhibited cytotoxicity against HEp-2 and HepG2 cells with IC50 values of 10 and 8 μg/mL, respectively.
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页码：15 / 18
页数：3
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