Potential targets for the development of new antifungal drugs

被引：0
作者：
Hao Su
Li Han
Xueshi Huang
机构：
[1] Northeastern University,Institute of Microbial Pharmaceuticals, College of Life and Health Sciences
来源：
The Journal of Antibiotics | 2018年 / 71卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
In recent years, incidences of invasive fungal infections have greatly increased, especially in immunosuppressed patients, but most today's antifungal drugs are not completely effective due to the development of drug resistance, as well as potential toxicity and adverse effects. Consequently, it is imperative to search for novel antifungal agents to combat fungal infections. This review will discuss the advances in the traditional antifungal therapy, and present an overview of novel strategies for the treatment of fungal infections. The papers presented here highlight new targets that could be exploited for development of new antifungal agents.
引用
收藏
页码：978 / 991
页数：13
相关论文
共 241 条
  • [1] Ikeh M(2017)Phosphate acquisition and virulence in human fungal pathogens Microorganisms 5 E48-87
  • [2] Ahmed Y(2017)Antifungal pharmacodynamics: Latin America’s perspective Braz J Infect Dis 21 79-476
  • [3] Quinn J(2018)Bafilomycin C1 exert antifungal effect through disturbing sterol biosynthesis in J Antibiot (Tokyo) 71 467-1490
  • [4] Gonzalez JM(2017)Recent advances in delivery of antifungal agents for therapeutic management of candidiasis Biomed Pharmacother 96 1478-606
  • [5] Rodriguez CA(2016)Novel strategies to fight Crit Rev Microbiol 42 594-63
  • [6] Agudelo M(2007) species infection Clin Microbiol Rev 20 133-50
  • [7] Zuluaga AF(2018)Epidemiology of invasive candidiasis: a persistent public health problem BMC Complement Altern Med 18 61-96
  • [8] Vesga O(2009)Effect of tt-farnesol and myricetin on in vitro biofilm formed by FEMS Yeast Res 9 1029-9
  • [9] Su H(2015) and Front Microbiol 6 1420-9
  • [10] Sawant B(2017)Antifungal drug resistance mechanisms in fungal pathogens from the perspective of transcriptional gene regulation Biochem Pharmacol 133 86-515
12345678910