Clinical and laboratory characteristics of patients with sickle-cell and autoimmune/connective tissue diseases

被引:0
作者
Salam Alkindi
Mustafa Al-Maini
Anil Pathare
机构
[1] Sultan Qaboos University,Department of Haematology
[2] Sultan Qaboos University,Department of Medicine
[3] Sultan Qaboos University Hospital,undefined
来源
Rheumatology International | 2012年 / 32卷
关键词
SCD; SLE; CTD; Autoimmune; Sickle; Connective; Anemia;
D O I
暂无
中图分类号
学科分类号
摘要
Patients with sickle-cell disease who develop autoimmune connective tissue disorders can present with similar clinical manifestations and/or complications making them indistinguishable. We report here a single-institution study on a cohort of 24 patients, with the above combination. The results suggest that there is often a significant delay in making the second diagnosis because of the overlapping clinical profile. It is emphasized that the clinician should be aware of and vigilant about such cases and should diligently follow up such cases to make an early diagnosis and start the appropriate treatment.
引用
收藏
页码:373 / 378
页数:5
相关论文
共 119 条
  • [1] Rahman A(2008)Systemic lupus erythromatosus N Engl J Med 358 929-939
  • [2] Isenberg D(2008)Characteristics and outcome of connective tissue diseases in patients with sickle cell disease : report of 30 patients Semin Arthritis Rheum 38 228-240
  • [3] Michel M(2010)Forecasting hemoglobinopathy burden through neonatal screening in omani neonates Hemoglobin 34 135-144
  • [4] Habib A(2003)Systemic lupus erythromatosus in children with sickle cell disease J Ped Hema/Oncol 25 668-671
  • [5] Godeau B(1992)Lack of evidence for altered complement and immunoglobulin levels in patients with sickle cell anaemia Scand J Clin Lab Invest 52 313-316
  • [6] Bachir D(1979)Sickle cell anemia complement and systemic lupus erythromatosus Arthritis Rheum 22 803-15
  • [7] Lahary A(1984)Serum autoantibodies in patients with sickle cell anemia Am J Med Sci 287 13-189
  • [8] Galacteros F(1990)Antinuclear antibodies in sickle cell disease Acta Haemtol 84 186-1178
  • [9] Fift-Mah A(1985)Systemic lupus erythromatosus in a child with sickle cell disease South Med J 88 1176-621
  • [10] Arfi S(1976)Systemic lupus erythromatosus and sickle cell anaemia BMJ 1 813-1031