Dopamine signaling modulates microglial NLRP3 inflammasome activation: implications for Parkinson’s disease

被引：0
作者：
Adrianne F. Pike
Francesca Longhena
Gaia Faustini
Jean-Marc van Eik
Iris Gombert
Maaike A. C. Herrebout
Mona M. H. E. Fayed
Michele Sandre
Tatiana Varanita
Charlotte E. Teunissen
Jeroen J. M. Hoozemans
Arianna Bellucci
Robert Veerhuis
Luigi Bubacco
机构：
[1] Amsterdam UMC,Department of Clinical Chemistry, Amsterdam Neuroscience, Neurochemistry Laboratory
[2] Vrije Universiteit Amsterdam,Pharmacology Division, Department of Molecular and Translational Medicine
[3] University of Brescia,Department of Biology
[4] University of Padua,Department of Pathology, Amsterdam Neuroscience, Neuropathology Laboratory
[5] Amsterdam UMC,Department of Psychiatry, Amsterdam Neuroscience
[6] Vrije Universiteit Amsterdam,undefined
[7] Amsterdam UMC,undefined
[8] Vrije Universiteit Amsterdam,undefined
来源：
Journal of Neuroinflammation | / 19卷
关键词：
Parkinson’s disease; NLRP3 inflammasome; Primary human microglia; Neuroinflammation; α-Synuclein; Dopamine; Potassium;
D O I：
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  • [1] Sgobio C(2019)Unbalanced calcium channel activity underlies selective vulnerability of nigrostriatal dopaminergic terminals in Parkinsonian mice Sci Rep 9 4857-830
  • [2] Sun L(2010)Neuropathology in Parkinson’s disease with mild cognitive impairment Acta Neuropathol 120 829-909
  • [3] Ding J(2003)Parkinson’s disease: mechanisms and models Neuron 39 889-211
  • [4] Herms J(2003)Staging of brain pathology related to sporadic Parkinson’s disease Neurobiol Aging 24 197-37
  • [5] Lovinger DM(2017)Pathological alpha-synuclein exacerbates the progression of Parkinson’s disease through microglial activation Toxicol Lett 265 30-542
  • [6] Cai H(2005)Aggregated alpha-synuclein activates microglia: a process leading to disease progression in Parkinson’s disease FASEB J 19 533-162
  • [7] Jellinger KA(1999)Parkinson’s disease, dementia with Lewy bodies and multiple system atrophy are alpha-synucleinopathies Parkinsonism Relat Disord 5 157-1109
  • [8] Dauer W(2019)Lewy pathology in Parkinson’s disease consists of crowded organelles and lipid membranes Nat Neurosci 22 1099-477
  • [9] Przedborski S(2014)Innate immune activation in neurodegenerative disease Nat Rev Immunol 14 463-934
  • [10] Braak H(2010)Mechanisms underlying inflammation in neurodegeneration Cell 140 918-38
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