A novel SLC12A3 gene homozygous mutation of Gitelman syndrome in an Asian pedigree and literature review

被引:0
作者
Q. Lü
Y. Zhang
C. Song
Z. An
S. Wei
J. Huang
L. Huang
L. Tang
N. Tong
机构
[1] West China Hospital of Sichuan University,Department of Endocrinology and Metabolism
[2] Sichuan University,West China School of Medicine
来源
Journal of Endocrinological Investigation | 2016年 / 39卷
关键词
SLC12A3 gene; Homozygous mutation; Gitelman Syndrome; Pedigree;
D O I
暂无
中图分类号
学科分类号
摘要
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页码:333 / 340
页数:7
相关论文
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Gitelman HJ(1966)A new familial disorder characterized by hypokalemia and hypomagnesemia Trans Assoc Am Physicians 79 221-235
[2]  
Graham JB(2000)Genetic variants of thiazide-sensitive NaCl-cotransporter in Gitelman’s syndrome and primary hypertension Hypertension 36 389-394
[3]  
Welt LG(1996)Novel molecular variants of the Na-Cl cotransporter gene are responsible for Gitelman syndrome Am J Hum Genet 59 1019-1026
[4]  
Melander O(1996)Gitelman’s variant of Bartter’s syndrome, inherited hypokalaemic alkalosis, is caused by mutations in the thiazide-sensitive Na-Cl cotransporter Nat Genet 12 24-30
[5]  
Orho-Melander M(2007)Gitelman’s syndrome: towards genotype-phenotype correlations? Pediatr Nephrol 22 326-332
[6]  
Bengtsson K(1996)Molecular cloning, expression pattern, and chromosomal localization of the human Na-Cl thiazide-sensitive cotransporter (SLC12A3) Genomics 35 486-493
[7]  
Mastroianni N(2002)Identification of fifteen novel mutations in the SLC12A3 gene encoding the Na-Cl Co-transporter in Italian patients with Gitelman syndrome Hum Mutat 20 78-177
[8]  
Bettinelli A(2013)Gitelman’s Syndrome: Asymptomatic Hypokalaemia in a Chinese Boy HK J Paediatr New Ser 18 174-551
[9]  
Bianchetti M(1995)Genetic heterogeneity in tubular hypomagnesemia-hypokalemia with hypocalcuria (Gitelman’s syndrome) Kidney Int 47 547-260
[10]  
Simon DB(2003)Recent advances in molecular genetics of hereditary magnesium-losing disorders J Am Soc Nephrol 14 249-1283