Stimuli-responsive electrospun nanofibers for drug delivery, cancer therapy, wound dressing, and tissue engineering

被引:0
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作者
Kai Chen
Yonghui Li
Youbin Li
Yinfeng Tan
Yingshuo Liu
Weisan Pan
Guoxin Tan
机构
[1] Hainan Medical University,Key Laboratory of Tropical Translational Medicine of Ministry of Education, Hainan provincial key laboratory of R&D on tropical herbs, Haikou Key Laboratory of Li Nationality Medicine, School of Pharmacy
[2] Hainan University,Key Laboratory of Tropical Biological Resources of Ministry of Education, School of Pharmacy
[3] Shenyang Pharmaceutical University,School of Pharmacy
关键词
Stimuli-responsive; Nanofibers; Electrospinning; Drug delivery; Biomedicine;
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摘要
The stimuli-responsive nanofibers prepared by electrospinning have become an ideal stimuli-responsive material due to their large specific surface area and porosity, which can respond extremely quickly to external environmental incitement. As an intelligent drug delivery platform, stimuli-responsive nanofibers can efficiently load drugs and then be stimulated by specific conditions (light, temperature, magnetic field, ultrasound, pH or ROS, etc.) to achieve slow, on-demand or targeted release, showing great potential in areas such as drug delivery, tumor therapy, wound dressing, and tissue engineering. Therefore, this paper reviews the recent trends of stimuli-responsive electrospun nanofibers as intelligent drug delivery platforms in the field of biomedicine.
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