Clinical Evaluation of the Analgesic Effect of Sustained Release Morphine Sulfate Microgranules in Patients with Terminal Cancer

被引：0

作者：

Guo-Zhu Xu

Zhi-Ji Cai

Yan-Ping Deng

Jun Hou

Guang-Ru Xie

Shu-Jun Liu

机构：

[1] Beijing Medical University,National Institute on Drug Dependence

[2] Hebei Cancer Institute,College of Oncology

[3] Tianjin Cancer Hospital,undefined

[4] Beijing Medical University,undefined

来源：

Clinical Drug Investigation | 1997年 / 14卷

关键词：

Adis International Limited; Pain Relief; Sustained Release; Numerical Rating Scale; Drug Invest;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

A randomised controlled clinical trial evaluating the analgesic effect of capsules containing sustained release (SR) morphine sulfate microgranules (M-Eslon®) was conducted in 120 patients with terminal cancer and moderate or severe pain. SR morphine sulfate as a tablet formulation (MS-Contin®) was used as the control drug. Both drugs were administered orally at dosages of 20mg (lower dosage) or 30mg (higher dosage) every 12 hours for 7 days. The parameters for pain assessment were pain intensity, evaluated on a 1 to 10 numerical rating scale, and pain relief (PAR), evaluated on a 5-grade scale.

引用

页码：34 / 42

页数：8