Cardiovascular changes after administration of aerosolized salbutamol in horses: five cases

被引：0
作者：
Daniela Casoni
Claudia Spadavecchia
Chiara Adami
机构：
[1] Department of Clinical Veterinary Sciences of the Vetsuisse Faculty of Berne,Anaesthesiology and Pain Therapy Division
来源：
Acta Veterinaria Scandinavica | / 56卷
关键词：
Salbutamol; Horse; Anesthesia; Cardiovascular side effects;
D O I：
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学科分类号：
摘要：
Prevention and treatment of intraoperative hypoxemia in horses is difficult and both efficacy and safety of therapeutic maneuvers have to be taken into account. Inhaled salbutamol has been suggested as treatment of hypoxia in horses during general anesthesia, due to safety and ease of the technique. The present report describes the occurrence of clinically relevant unwanted cardiovascular effects (i.e. tachycardia and blood pressure modifications) in 5 horses undergoing general anesthesia in dorsal recumbency after salbutamol inhalation. Balanced anesthesia based on inhalation of isoflurane in oxygen or oxygen and air and continuous rate infusion (CRI) of lidocaine, romifidine, or combination of lidocaine and guaifenesine and ketamine was provided. Supportive measures were necessary to restore normal cardiovascular function in all horses but no long-term adverse effects were noticed in any of the cases.
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  • [1] Robertson SA(2002)Aerosolized salbutamol (albuterol) improves PaO Vet Anaesth Analg 29 212-218
  • [2] Bailey JE(1988) in hypoxaemic anaesthetized horses-a prospective clinical trial in 81 horses Zentralbl Veterinarmed A 35 54-62
  • [3] Nyman G(1989)Postural effects on blood gas tension, blood pressure, heart rate, ECG and respiratory rate during prolonged anesthesia in the horse Equine Vet J 21 274-281
  • [4] Funkquist B(1999)Ventilation-perfusion relationships in the anaesthetised horse J Am Vet Med Assoc 215 978-981
  • [5] Kvart C(1990)Predictors of arterial oxygen tension in anesthetized horses: 1,610 cases (1992–1994) Equine Vet J 22 317-324
  • [6] Nyman G(1993)Atelectasis causes gas exchange impairment in the anaesthetised horse Am J Vet Res 54 776-782
  • [7] Hedenstierna G(1998)Effects of clenbuterol hydrochloride on pulmonary gas exchange and hemodynamics in anesthetized horses Res Vet Sci 65 227-232
  • [8] Whitehair KJ(2010)The cardiopulmonary effects of clenbuterol when administered to dorsally recumbent halothane-anaesthetised ponies - failure to increase arterial oxygenation Br J Pharmacol 160 1048-1061
  • [9] Willits NH(2002)The selectivity of beta-adrenoceptor agonists at human β Eur Resp J 20 524-528
  • [10] Nyman G(1999)-, β Am J Vet Res 60 689-693
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