HEPBURN - investigating the efficacy and safety of nebulized heparin versus placebo in burn patients with inhalation trauma: study protocol for a multi-center randomized controlled trial

被引：0
作者：
Gerie J Glas
Johannes Muller
Jan M Binnekade
Berry Cleffken
Kirsten Colpaert
Barry Dixon
Nicole P Juffermans
Paul Knape
Marcel M Levi
Bert G Loef
David P Mackie
Manu Malbrain
Marcus J Schultz
Koenraad F van der Sluijs
机构：
[1] Academic Medical Center,Laboratory of Experimental Intensive Care and Anesthesiology (L · E · I C · A), Department of Intensive Care Medicine
[2] Academic Medical Center,Department of Intensive Care Medicine
[3] University Hospital Gasthuisberg,Department of Intensive Care
[4] Maasstad Hospital,Department of Intensive Care
[5] Ghent University Hospital,Department of Intensive Care
[6] St Vincent’s Hospital,Department of Intensive Care
[7] Red Cross Hospital,Department of Intensive Care
[8] Academic Medical Center,Department of Internal Medicine
[9] Martini Hospital,Department of Intensive Care
[10] Ziekenhuis Netwerk Antwerpen - Stuivenberg,Department of Intensive Care
来源：
Trials | / 15卷
关键词：
Inhalation trauma; Pulmonary coagulopathy; Nebulization; Heparin; Mechanical ventilation;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 330 条
  • [1] Bloemsma GC(2008)Mortality and causes of death in a burn centre Burns 34 1103-1107
  • [2] Dokter J(2010)Assessing the severity of inhalation injuries in adults Burns 36 212-216
  • [3] Boxma H(2005)Inhalational and acute lung injury Shock 24 82-87
  • [4] Oen IM(2010)The biology of burn injury Exp Dermatol 19 777-783
  • [5] Hassan Z(2011)Pulmonary activation of coagulation and inhibition of fibrinolysis after burn injuries and inhalation trauma J Trauma 70 1389-1397
  • [6] Wong JK(2007)Aerosolized anticoagulants ameliorate acute lung injury in sheep after exposure to burn and smoke inhalation Crit Care Med 35 2805-2810
  • [7] Bush J(2008)Combined anticoagulants ameliorate acute lung injury in sheep after burn and smoke inhalation Clin Sci (Lond) 114 321-329
  • [8] Bayat A(2008)Pulmonary changes in a mouse model of combined burn and smoke inhalation-induced injury J Appl Physiol 105 678-684
  • [9] Dunn KW(2002)Heparin nebulization attenuates acute lung injury in sepsis following smoke inhalation in sheep Shock 18 236-241
  • [10] Traber DL(2009)Management of burn injuries - recent developments in resuscitation, infection control and outcomes research Scand J Trauma Resusc Emerg Med 17 14-256
12345678910