Serum methylation of GALNT9, UPF3A, WARS, and LDB2 as noninvasive biomarkers for the early detection of colorectal cancer and advanced adenomas

被引：0

作者：

María Gallardo-Gómez

Mar Rodríguez-Girondo

Núria Planell

Sebastian Moran

Luis Bujanda

Ane Etxart

Antoni Castells

Francesc Balaguer

Rodrigo Jover

Manel Esteller

Joaquín Cubiella

David Gómez-Cabrero

Loretta De Chiara

机构：

[1] CINBIO,Department of Biochemistry, Genetics and Immunology

[2] Universidade de Vigo,Translational Oncology Group, Galicia Sur Health Research Institute (IIS Galicia Sur)

[3] CINBIO,Department of Medical Statistics and Bioinformatics

[4] Universidade de Vigo,Translational Bioinformatics Unit, Navarrabiomed, Complejo Hospitalario de Navarra (CHN)

[5] SERGAS-UVIGO,Cancer Epigenetics and Biology Program (PEBC)

[6] Leiden University Medical Centre,Department of Gastroenterology, Biodonostia Health Research Institute, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd)

[7] Universidad Pública de Navarra (UPNA),Department of Surgery

[8] IdiSNA,Gastroenterology Department

[9] Bellvitge Biomedical Research Institute (IDIBELL),Department of Gastroenterology

[10] Universidad del País Vasco (UPV/EHU),Physiological Sciences Department, School of Medicine and Health Sciences

[11] Hospital Universitario Donostia,Department of Gastroenterology

[12] Hospital Clínic,Biological & Environmental Sciences & Engineering Division

[13] IDIBAPS,Mucosal & Salivary Biology Division

[14] CIBERehd,Servicio de Medicina Digestiva. ISABIAL. Universidad Miguel Hernández

[15] University of Barcelona,Cancer Genomics Group, Galicia Sur Health Research Institute (IIS Galicia Sur)

[16] Hospital General Universitario de Alicante,undefined

[17] Josep Carreras Leukaemia Research Institute (IJC),undefined

[18] Centro de Investigacion Biomedica en Red Cancer (CIBERONC),undefined

[19] Institucio Catalana de Recerca i Estudis Avançats (ICREA),undefined

[20] University of Barcelona (UB),undefined

[21] Complexo Hospitalario Universitario de Ourense,undefined

[22] Instituto de Investigación Biomédica Galicia Sur,undefined

[23] Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd),undefined

[24] King Abdullah University of Science & Technology,undefined

[25] King’s College London Dental Institute,undefined

[26] Hospital General Universitario Dr. Balmis,undefined

[27] SERGAS-UVIGO,undefined

来源：

Clinical Epigenetics | / 15卷

关键词：

Advanced adenomas; Colorectal cancer; Cancer prevention; Circulating cell-free DNA; DNA methylation; Liquid biopsy; Screening; Serum;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

共 211 条

[11]

Dominitz JA(2018)The impact of sample type and procedural attributes on relative acceptability of different colorectal cancer screening regimens Patient Prefer Adherence 12 1825-429

[12]

Kahi C(2014)Improving compliance to colorectal cancer screening using blood and stool based tests in patients refusing screening colonoscopy in Germany BMC Gastroenterol 14 1-3418

[13]

Schoen RE(2021)Updates on clinical use of liquid biopsy in colorectal cancer screening, diagnosis, follow-up, and treatment guidance Front Cell Develop Biol 9 660924-10

[14]

Senore C(2017)Abnormal DNA methylation as a cell-free circulating DNA biomarker for colorectal cancer detection: a review of literature World J Gastrointest Oncol 9 142-15

[15]

Basu P(2014)Differences in DNA methylation signatures reveal multiple pathways of progression from adenoma to colorectal cancer Gastroenterology 147 418-22

[16]

Anttila A(2018)Cell-of-Origin DNA methylation signatures are maintained during colorectal carcinogenesis Cell Rep 23 3407-35

[17]

Ponti A(2018)A new approach to epigenome-wide discovery of non-invasive methylation biomarkers for colorectal cancer screening in circulating cell-free DNA using pooled samples Clin Epigenetics 10 1-13897

[18]

Tomatis M(2013)A modified Phenol-chloroform extraction method for isolating circulating cell free DNA of tumor patients J Nucleic Acids Investig 4 e1-732

[19]

Vale DB(2019)Guidance for DNA methylation studies: statistical insights from the Illumina EPIC array BMC Genom 20 1-9

[20]

Lee JK(2010)Regularization paths for generalized linear models via coordinate descent J Stat Softw 33 1-4281

← 1 2 3 4 5 6 7 8 9 10 →