Serum methylation of GALNT9, UPF3A, WARS, and LDB2 as noninvasive biomarkers for the early detection of colorectal cancer and advanced adenomas

被引:0
作者
María Gallardo-Gómez
Mar Rodríguez-Girondo
Núria Planell
Sebastian Moran
Luis Bujanda
Ane Etxart
Antoni Castells
Francesc Balaguer
Rodrigo Jover
Manel Esteller
Joaquín Cubiella
David Gómez-Cabrero
Loretta De Chiara
机构
[1] CINBIO,Department of Biochemistry, Genetics and Immunology
[2] Universidade de Vigo,Translational Oncology Group, Galicia Sur Health Research Institute (IIS Galicia Sur)
[3] CINBIO,Department of Medical Statistics and Bioinformatics
[4] Universidade de Vigo,Translational Bioinformatics Unit, Navarrabiomed, Complejo Hospitalario de Navarra (CHN)
[5] SERGAS-UVIGO,Cancer Epigenetics and Biology Program (PEBC)
[6] Leiden University Medical Centre,Department of Gastroenterology, Biodonostia Health Research Institute, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd)
[7] Universidad Pública de Navarra (UPNA),Department of Surgery
[8] IdiSNA,Gastroenterology Department
[9] Bellvitge Biomedical Research Institute (IDIBELL),Department of Gastroenterology
[10] Universidad del País Vasco (UPV/EHU),Physiological Sciences Department, School of Medicine and Health Sciences
[11] Hospital Universitario Donostia,Department of Gastroenterology
[12] Hospital Clínic,Biological & Environmental Sciences & Engineering Division
[13] IDIBAPS,Mucosal & Salivary Biology Division
[14] CIBERehd,Servicio de Medicina Digestiva. ISABIAL. Universidad Miguel Hernández
[15] University of Barcelona,Cancer Genomics Group, Galicia Sur Health Research Institute (IIS Galicia Sur)
[16] Hospital General Universitario de Alicante,undefined
[17] Josep Carreras Leukaemia Research Institute (IJC),undefined
[18] Centro de Investigacion Biomedica en Red Cancer (CIBERONC),undefined
[19] Institucio Catalana de Recerca i Estudis Avançats (ICREA),undefined
[20] University of Barcelona (UB),undefined
[21] Complexo Hospitalario Universitario de Ourense,undefined
[22] Instituto de Investigación Biomédica Galicia Sur,undefined
[23] Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd),undefined
[24] King Abdullah University of Science & Technology,undefined
[25] King’s College London Dental Institute,undefined
[26] Hospital General Universitario Dr. Balmis,undefined
[27] SERGAS-UVIGO,undefined
来源
Clinical Epigenetics | / 15卷
关键词
Advanced adenomas; Colorectal cancer; Cancer prevention; Circulating cell-free DNA; DNA methylation; Liquid biopsy; Screening; Serum;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 211 条
[1]  
Bray F(2018)Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries CA Cancer J Clin 68 394-424
[2]  
Ferlay J(2019)Cancer statistics, 2019 CA Cancer J Clin 69 7-34
[3]  
Soerjomataram I(2020)Strategies for colorectal cancer screening Gastroenterology 158 418-432
[4]  
Siegel RL(2019)Performance of colorectal cancer screening in the European union member states: data from the second European screening report Gut 68 1232-1244
[5]  
Torre LA(2014)Accuracy of fecal immunochemical tests for colorectal cancer: systematic review and meta-analysis Ann Intern Med 160 171-29
[6]  
Jemal A(2019)Performance characteristics of fecal immunochemical tests for colorectal cancer and advanced adenomatous polyps: a systematic review and meta-analysis Ann Intern Med 170 319-2693
[7]  
Siegel RL(2016)Does low threshold value use improve proximal neoplasia detection by fecal immunochemical test Dig Dis Sci. 61 2685-610
[8]  
Miller KD(2016)Screening for colorectal cancer: updated evidence report and systematic review for the US preventive services task force JAMA 315 2576-1836
[9]  
Jemal A(2017)The SEPT9 gene methylation assay is capable of detecting colorectal adenoma in opportunistic screening Epigenomics 9 599-8
[10]  
Ladabaum U(2017)The performance of the SEPT9 gene methylation assay and a comparison with other CRC screening tests: a meta-analysis Sci Rep 7 3032-152