EFEMP2 upregulates PD-L1 expression via EGFR/ERK1/2/c-Jun signaling to promote the invasion of ovarian cancer cells

被引：0
|
作者：
Xin Shen
Xuli Jin
Shuang Fang
Jie Chen
机构：
[1] Shandong University,Department of Maternal and Child Health, School of Public Health, Cheeloo College of Medicine
[2] Shandong University,Department of Epidemiology, School of Public Health, Cheeloo College of Medicine
[3] Jinan Medical Center Management Committee,undefined
来源：
Cellular & Molecular Biology Letters | / 28卷
关键词：
Ovarian cancer; EFEMP2; PD-L1; EGFR; ERK1/2/c-Jun pathway; Trametinib; Afatinib;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [41] Ovarian cancer ascites increase Mcl-1 expression in tumor cells through ERK1/2-Elk-1 signaling to attenuate TRAIL-induced apoptosis
    Goncharenko-Khaider, Nadzeya
    Matte, Isabelle
    Lane, Denis
    Rancourt, Claudine
    Piche, Alain
    MOLECULAR CANCER, 2012, 11
  • [42] Ovarian cancer ascites increase Mcl-1 expression in tumor cells through ERK1/2-Elk-1 signaling to attenuate TRAIL-induced apoptosis
    Nadzeya Goncharenko-Khaider
    Isabelle Matte
    Denis Lane
    Claudine Rancourt
    Alain Piché
    Molecular Cancer, 11
  • [43] Cancer-associated fibroblasts promote cell growth by activating ERK5/PD-L1 signaling axis in colorectal cancer
    Zhang, Mengyan
    Shi, Ran
    Guo, Zhongying
    He, Jingdong
    PATHOLOGY RESEARCH AND PRACTICE, 2020, 216 (04)
  • [44] Hexokinase 2 Regulates Ovarian Cancer Cell Migration, Invasion and Sternness via FAK/ERK1/2/MMP9/NANOG/SOX9 Signaling Cascades
    Siu, Michelle K. Y.
    Jiang, Yu-Xin
    Wang, Jing-Jing
    Leung, Thomas H. Y.
    Han, Chae Young
    Tsang, Benjamin K.
    Cheung, Annie N. Y.
    Ngan, Hextan Y. S.
    Chan, Karen K. L.
    CANCERS, 2019, 11 (06)
  • [45] AKT/mTOR Signal Cascade and Expression of PD-1, PD-L1, and PD-L2 in Gastric Cancer
    Spirina, L. V.
    Avgustinovich, A. V.
    Afanas'ev, S. G.
    Kondakova, I. V.
    Volkov, M. Yu.
    Dobrodeev, A. Yu.
    Boronkina, A. I.
    BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2020, 170 (01) : 75 - 78
  • [46] GDNF secreted by nerves enhances PD-L1 expression via JAK2-STAT1 signaling activation in HNSCC
    Lin, Chengzhong
    Cao, Wei
    Ren, Zhenhu
    Tang, Yu
    Zhang, Chunye
    Yang, Rong
    Chen, Yiming
    Liu, Zheqi
    Peng, Canbang
    Wang, Lizhen
    Wang, Xu
    Ji, Tong
    ONCOIMMUNOLOGY, 2017, 6 (11):
  • [47] JAK2 and PD-L1 Amplification Enhance the Dynamic Expression of PD-L1 in Triple-negative Breast Cancer
    Chen, Meixuan
    Pockaj, Barbara
    Andreozzi, Mariacarla
    Barrett, Michael T.
    Krishna, Sri
    Eaton, Seron
    Niu, Ruifang
    Anderson, Karen S.
    CLINICAL BREAST CANCER, 2018, 18 (05) : E1205 - E1215
  • [48] Divergent Cellular Expression Patterns of PD-L1 and PD-L2 Proteins in Breast Cancer
    Jorns, Julie M.
    Sun, Yunguang
    Kamaraju, Sailaja
    Cheng, Yee Chung
    Kong, Amanda
    Yen, Tina
    Patten, Caitlin R.
    Cortina, Chandler S.
    Chitambar, Christopher R.
    Rui, Hallgeir
    Chaudhary, Lubna N.
    JOURNAL OF PERSONALIZED MEDICINE, 2024, 14 (05):
  • [49] EZH2 regulates PD-L1 expression via HIF-1α in non-small cell lung cancer cells
    Zhao, Yuetao
    Wang, Xin-Xin
    Wu, Wei
    Long, Haixia
    Huang, Jiani
    Wang, Zhongyu
    Li, Tao
    Tang, Shu
    Zhu, Bo
    Chen, Degao
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, 517 (02) : 201 - 209
  • [50] EGFR-TKI resistance promotes immune escape in lung cancer via increased PD-L1 expression
    Shunli Peng
    Rong Wang
    Xiaojuan Zhang
    Yueyun Ma
    Longhui Zhong
    Ke Li
    Akihiro Nishiyama
    Sachiko Arai
    Seiji Yano
    Wei Wang
    Molecular Cancer, 18
12345