EFEMP2 upregulates PD-L1 expression via EGFR/ERK1/2/c-Jun signaling to promote the invasion of ovarian cancer cells

被引：0
|
作者：
Xin Shen
Xuli Jin
Shuang Fang
Jie Chen
机构：
[1] Shandong University,Department of Maternal and Child Health, School of Public Health, Cheeloo College of Medicine
[2] Shandong University,Department of Epidemiology, School of Public Health, Cheeloo College of Medicine
[3] Jinan Medical Center Management Committee,undefined
来源：
Cellular & Molecular Biology Letters | / 28卷
关键词：
Ovarian cancer; EFEMP2; PD-L1; EGFR; ERK1/2/c-Jun pathway; Trametinib; Afatinib;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [21] Infiltration of T cells promotes the metastasis of ovarian cancer cells via the modulation of metastasis-related genes and PD-L1 expression
    Jing-Jing Wang
    Michelle Kwan-Yee Siu
    Yu-Xin Jiang
    David Wai Chan
    Annie Nga-Yin Cheung
    Hextan Yuen-Sheung Ngan
    Karen Kar-Loen Chan
    Cancer Immunology, Immunotherapy, 2020, 69 : 2275 - 2289
  • [22] Inhibitors of PD-1/PD-L1 and ERK1/2 impede the proliferation of receptor positive and triple-negative breast cancer cell lines
    Braeutigam, Karen
    Kabore-Wolff, Elodie
    Hussain, Ahmad Fawzi
    Polack, Stephan
    Rody, Achim
    Hanker, Lars
    Koester, Frank
    JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2021, 147 (10) : 2923 - 2933
  • [23] Metformin Suppresses Both PD-L1 Expression in Cancer Cells and Cancer-Induced PD-1 Expression in Immune Cells to Promote Antitumor Immunity
    Park, Su Hwan
    Lee, Juheon
    Yun, Hye Jin
    Kim, Seok-Ho
    Lee, Jong-Ho
    ANNALS OF LABORATORY MEDICINE, 2024, 44 (05) : 426 - 436
  • [24] c-Jun transcriptionally regulates alpha 1, 2-fucosyltransferase 1 (FUT1) in ovarian cancer
    Gao, Na
    Liu, Juanjuan
    Liu, Dawo
    Hao, Yingying
    Yan, Limei
    Ma, Yanan
    Zhuang, Huiyu
    Hu, Zhenhua
    Gao, Jian
    Yang, Zhihai
    Shi, Hong
    Lin, Bei
    BIOCHIMIE, 2014, 107 : 286 - 292
  • [25] Polysaccharide Peptide Induced Colorectal Cancer Cells Apoptosis by Down-Regulating EGFR and PD-L1 Expression
    Lin Jian
    He Zhicheng
    Liu Shubai
    IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH, 2022, 21 (01):
  • [26] Programmed death ligand-1 regulates angiogenesis and metastasis by participating in the c-JUN/VEGFR2 signaling axis in ovarian cancer
    Yang, Yufei
    Xia, Lingfang
    Wu, Yong
    Zhou, Hongyu
    Chen, Xin
    Li, Haoran
    Xu, Midie
    Qi, Zihao
    Wang, Ziliang
    Sun, Huizhen
    Cheng, Xi
    CANCER COMMUNICATIONS, 2021, 41 (06) : 511 - 527
  • [27] A natural ent-kaurane diterpenoid induces antiproliferation in ovarian cancer cells via ERK1/2 regulation and inhibition of cellular migration and invasion
    Lee, Jin Sun
    Lee, Myung Sun
    Cha, Eun Young
    Phuong Thien Thuong
    Sul, Ji Young
    Park, Jun Beom
    Ko, Young Bok
    MOLECULAR MEDICINE REPORTS, 2018, 18 (04) : 3898 - 3906
  • [28] AKT-STAT3 Pathway as a Downstream Target of EGFR Signaling to Regulate PD-L1 Expression on NSCLC cells
    Abdelhamed, Sherif
    Ogura, Keisuke
    Yokoyama, Satoru
    Saiki, Ikuo
    Hayakawa, Yoshihiro
    JOURNAL OF CANCER, 2016, 7 (12): : 1579 - 1586
  • [29] FAM83A drives PD-L1 expression via ERK signaling and FAM83A/PD-L1 co-expression correlates with poor prognosis in lung adenocarcinoma
    Zhou, Fengrui
    Wang, Xin
    Liu, Fang
    Meng, Qingwei
    Yu, Yan
    INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY, 2020, 25 (09) : 1612 - 1623
  • [30] Propofol affects the biological behavior of ovarian cancer SKOV3 cells via ERK1/2-MMP-2/9 signaling pathway
    Yin, Ruchang
    Zhang, Chunyan
    Gen, Aizhi
    Li, Yanxiao
    Yang, Hailei
    Tian, Xin
    Chi, Yasong
    TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH, 2020, 19 (02) : 233 - 238
12345