Accuracy of Stool Antigen Test in Posteradication Assessment of Helicobacter pylori Infection

被引:0
作者
Gianpiero Manes
Antonio Balzano
Gaetano Iaquinto
Chiara Ricci
Maria Maddalena Piccirillo
Nicola Giardullo
Anna Todisco
Maurizio Lioniello
Dino Vaira
机构
[1] Cardarelli Hospital,Department of Gastroenterology
[2] San G. Moscati Hospital,Department of Gastroenterology
[3] University of Bologna,Clinica Medical
[4] Cardarelli Hospital,Central Laboratory
[5] San G. Moscati Hospital,Central Laboratory
来源
Digestive Diseases and Sciences | 2001年 / 46卷
关键词
stool; antigen; [; C]urea breath test; treatment outcome;
D O I
暂无
中图分类号
学科分类号
摘要
Our aim was to evaluate the accuracy of HpSA test in the diagnosis of Helicobacter pylori infection after the end of eradication therapy. In all 106 H. pylori-positive patients (55 men and 51 women, mean age 51 years, range 19–82) were treated with a course of eradicating regimen. [13C]Urea breath test (UBT) and HpSA were performed four weeks after stopping the treatment. The diagnostic accuracy of HpSA was evaluated in comparison with the results of [13C]UBT. In 90 patients (85%) H. pylori was eradicated according to [13C]urea breath test. After eradication, sensitivity of HpSA was 87.5%, specificity 95.5%, positive predictive value 77.8%, negative predictive value 97.7%, and diagnostic accuracy 94.3%. HpSA is a valuable test in the posteradication assessment of H. pylori infection.
引用
收藏
页码:2440 / 2444
页数:4
相关论文
共 128 条
[11]  
Duhmke E(2000) in faeces with a new enzyme immunassay method: preliminary results Dig Liver Dis 32 285-206
[12]  
Muller-Hermelink HK(2000)GNJ, European Am J Gastroenterol 95 2200-3714
[13]  
Wilms K(2001) HpSA study Group: Noninvasive antigen-based assay for assessing Aliment Pharmacol Ther 15 203-13
[14]  
Lassen AT(2000) eradication. A European multicenter study J Clin Microbiol 38 3710-33
[15]  
Pedersen FM(1997)Stool test may defeat breath test: New faecal antigen detects Gut 41 8-1698
[16]  
Bytzer P(1999) infection and eradication Lancet 354 30-694
[17]  
de-Muckadell OBS(2000)Diagnostic accuracy of a new non-invasive enzyme immunoassay for detecting Am J Gastroenterol 95 1691-undefined
[18]  
Leodolter A(1996) in stools after eradication therapy Am J Gastroenterol 91 690-undefined
[19]  
Dominguez-Munoz JE(undefined)Discrepancy between Helicobacter pylori stool test antigen assay and urea breath test in the detection of undefined undefined undefined-undefined
[20]  
von Arnim U(undefined) infection undefined undefined undefined-undefined