The Circadian Clocks, Oscillations of Pain-Related Mediators, and Pain

被引：0
作者：
Yanhao Chu
Hongwen He
Qing Liu
Shilin Jia
Wenguo Fan
Fang Huang
机构：
[1] Sun Yat-sen Uni-versity,Hospital of Stomatology, Guanghua School of Stomatology
[2] Guangdong Provincial Key Laboratory of Stomatology,undefined
来源：
Cellular and Molecular Neurobiology | 2023年 / 43卷
关键词：
Circadian clocks; Molecular clocks; Diurnal oscillations; Pain; Circadian pain;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The circadian clock is a biochemical oscillator that is synchronized with solar time. Normal circadian rhythms are necessary for many physiological functions. Circadian rhythms have also been linked with many physiological functions, several clinical symptoms, and diseases. Accumulating evidence suggests that the circadian clock appears to modulate the processing of nociceptive information. Many pain conditions display a circadian fluctuation pattern clinically. Thus, the aim of this review is to summarize the existing knowledge about the circadian clocks involved in diurnal rhythms of pain. Possible cellular and molecular mechanisms regarding the connection between the circadian clocks and pain are discussed.
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页码：511 / 523
页数：12
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