Urate inhibits microglia activation to protect neurons in an LPS-induced model of Parkinson’s disease

被引:0
作者
Li-Hui Bao
Ya-Nan Zhang
Jian-Nan Zhang
Li Gu
Hui-Min Yang
Yi-Ying Huang
Ning Xia
Hong Zhang
机构
[1] Capital Medical University,Department of Neurobiology, School of Basic Medical Sciences, Beijing Institute for Brain Disorders and Key Laboratory for Neurodegenerative Disorders of the Ministry of Education
来源
Journal of Neuroinflammation | / 15卷
关键词
Urate; Microglia; Inflammation; Urate transporter; Parkinson’s disease;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 309 条
[1]  
McGeer PL(1988)Rate of cell death in parkinsonism indicates active neuropathological process Ann Neurol 24 574-576
[2]  
Itagaki S(2000)Cytokines in Parkinson’s disease J Neural Transm Supp 58 143-151
[3]  
Akiyama H(1994)Interleukin-1β, interleukin-6, epidermal growth factor and transforming growth factor-α are elevated in the brain from parkinsonian patients Neurosci Lett 180 147-150
[4]  
McGeer EG(2005)Inflammatory process as a determinant factor for the degeneration of substantia nigra dopaminergic neurons J Neural Transm 112 111-119
[5]  
Nagatsu T(2008)Microglia Curr Biol 18 R506-R508
[6]  
Mogi M(2010)Microglial activation & chronic neurodegeneration Neurotherapeutics 7 354-365
[7]  
Ichinose H(2012)Protection of dopaminergic cells by urate requires its accumulation in astrocytes J Neurochem 123 172-181
[8]  
Togari A(2010)Urate: a novel biomarker of Parkinson’s disease risk, diagnosis and prognosis Biomark Med 5 701-712
[9]  
Mogi M(2008)Uric acid and neuroprotection Stroke 39 e126-526
[10]  
Harada M(2016)Prospective study of plasma urate and risk of Parkinson disease in men and women Neurology 86 520-380