Usefullness of low-priming-volume cardiopulmonary bypass circuits and dilutional ultrafiltration in neonatal open-heart surgery

被引：11

作者：

Fukumura F. ^{[1
,3
]}

Kado H. ^{[1
]}

Imoto Y. ^{[1
]}

Shiokawa Y. ^{[1
]}

Minami K. ^{[1
]}

Murakami J. ^{[1
]}

Yasui H. ^{[2
]}

机构：

[1] Department of Cardiovascular Surgery, Fukuoka Children's Hospital, Fukuoka

[2] Department of Cardiovascular Surgery, Faculty of Medicine, Kyushu University, Fukuoka

[3] Department of Cardiovascular Surgery, Aso-Iizuka Hospital, Iizuka 820-8505

来源：

Journal of Artificial Organs | 2004年 / 7卷 / 1期

关键词：

Cardiopulmonary bypass; Neonate;

D O I：

10.1007/s10047-003-0241-9

中图分类号：

学科分类号：

摘要：

In neonate open-heart surgery, cardiopulmonary bypass (CPB) with extreme hemodilution induces an increased capillary permeability and accumulation of extravascular fluid, resulting in organ dysfunction. We evaluated the effects of a reduced priming volume for CPB and dilutional ultrafiltration (DUF) during neonatal open-heart surgery. Nineteen consecutive neonates with complete transposition of the great arteries who underwent an arterial switch operation were retrospectively assigned into two groups: the high-priming-volume circuit group (group A, n = 9) and the low-priming-volume circuit group (group B, n = 10). Patients in group B underwent surgery with a miniaturized CPB circuit and using the DUF technique. The priming volume of group B was nearly two-thirds that of group A. The water balance value after CPB and surgery was significantly lower in group B (-126 ± 118 ml, -116 ± 116 ml) than in group A (88 ± 218 ml, 83 ± 165 ml). Systolic blood pressure just after CPB was higher in group B (67.9 ± 9.1 mmHg) than in group A (55.4 ± 10.3 mmHg). Postoperative ventilatory support was shorter in group B (45 ± 19 h) than in group A (68 ± 27 h). In neonatal cardiac surgery, low-priming-volume CPB circuits and DUF improve the water balance during surgery and may attenuate any inflammatory reaction, which would help preserve postoperative organ function.

引用

页码：9 / 12

页数：3

共 9 条

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