Target delivery of a PD-1-TREM2 scFv by CAR-T cells enhances anti-tumor efficacy in colorectal cancer

被引:0
作者
Jian Chen
Tianchuan Zhu
Guanmin Jiang
Qi Zeng
Zhijian Li
Xi Huang
机构
[1] The Fifth Affiliated Hospital of Sun Yat-sen University,Center for Infection and Immunity and Guangdong Provincial Engineering Research Center of Molecular Imaging
[2] The Fifth Affiliated Hospital of Sun Yat-sen University,Department of Clinical Laboratory
[3] The Fifth Affiliated Hospital of Sun Yat-sen University,Department of Oncology
[4] The Fourth People’s Hospital of Foshan,undefined
来源
Molecular Cancer | / 22卷
关键词
CAR-T; TREM2; PD-1; Colorectal cancer; Tumor microenvironment; Single-chain variable fragment (scFv);
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