Vitamin D and systemic lupus erythematosus: state of the art

被引：0
作者：
Laiana Schneider
Amanda Senna Pereira dos Santos
Marcele Santos
Rafael Mendonça da Silva Chakr
Odirlei Andre Monticielo
机构：
[1] Universidade Federal do Rio Grande do Sul,Division of Rheumatology, Hospital de Clínicas de Porto Alegre
来源：
Clinical Rheumatology | 2014年 / 33卷
关键词：
25-Hydroxyvitamin D deficiency; Supplementation; Systemic lupus erythematosus; Vitamin D;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Systemic lupus erythematosus (SLE) is a systemic inflammatory disease associated with genetic, environmental, hormonal, and immunological factors. One of these factors is vitamin D deficiency. Vitamin D plays many roles in the immune system. Several studies have suggested a potential role in the development of autoimmune diseases. SLE patients have low serum levels of vitamin D, which increase the possibility of an association between vitamin deficiency and disease onset and evolution. This review of the literature presents an analysis of the aspects related to the immunoregulatory effects of vitamin D and its importance for SLE, as well as the recommendations for vitamin D supplementation in these patients.
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页码：1033 / 1038
页数：5
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