Preclinical assessment of the distribution, metabolism, and excretion of S-propargyl-cysteine, a novel H2S donor, in Sprague-Dawley rats

被引:0
作者
Yuan-ting Zheng
Jian-hua Zhu
Guo Ma
Qing Zhu
Ping Yang
Bo Tan
Jin-lian Zhang
Hai-xing Shen
Jia-lin Xu
Yi-zhun Zhu
Wei-min Cai
机构
[1] School of Pharmacy,Department of Clinical Pharmacy
[2] Fudan University,Department of Radiopharmacy
[3] School of Pharmacy,Department of Pharmacology
[4] Fudan University,undefined
[5] School of Pharmacy and Institute of Biomedical Sciences,undefined
[6] Fudan University,undefined
[7] Analytical and Testing Center,undefined
[8] School of Pharmacy,undefined
[9] Fudan University,undefined
来源
Acta Pharmacologica Sinica | 2012年 / 33卷
关键词
hydrogen sulfide (H; S); -propargyl-cysteine; pharmacokinetics; distribution; metabolism; excretion; disposition;
D O I
暂无
中图分类号
学科分类号
摘要
引用
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页码:839 / 844
页数:5
相关论文
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  • [1] Abe K(1996)The possible role of hydrogen sulfide as an endogenous neuromodulator J Neurosci 16 1066-71
  • [2] Kimura H(2003)The gasotransmitter role of hydrogen sulfide Antioxid Redox Signal 5 493-501
  • [3] Wang R(2000)Evidence that hydrogen sulphide can modulate hypothalamo-pituitary-adrenal axis function: J Neuroendoctinol 12 225-33
  • [4] Dello Russo C(2007) and J Hypertens 25 2100-4
  • [5] Tringali G(2006) studies in the rats Carcinogenesis 27 2180-9
  • [6] Ragazzoni E(2006)The novel gaseous vasorelaxant hydrogen sulfide inhibits angiotensin-converting enzyme activity of endothelial cells Am J Physiol Cell Physiol 291 C503-10
  • [7] Maggiano N(2008)A novel anticancer effect of garlic derivatives: inhibition of cancer cell invasion through restoration of E-cadherin expression Free Radic Res 42 892-902
  • [8] Menini E(2005)Mechanism of induction of pancreatic acinar cell apoptosis by hydrogen sulfide Nat Prod Rep 22 351-68
  • [9] Vairano M(2009)Lipid peroxidation, mitochondrial dysfunction and neurochemical and behavioural deficits in different neurotoxic models: protective role of J Cardiovasc Pharmacol 54 139-46
  • [10] Laggner H(2010)-allylcysteine Antioxid Redox Signal 12 1155-65