Mechanisms of single-stranded DNA-binding protein functioning in cellular DNA metabolism

被引：0
作者：
P. E. Pestryakov
O. I. Lavrik
机构：
[1] Siberian Branch of the Russian Academy of Sciences,Institute of Chemical Biology and Fundamental Medicine
来源：
Biochemistry (Moscow) | 2008年 / 73卷
关键词：
SSB proteins; replication protein A; protein-DNA complexes; DNA replication; DNA repair;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
This review deals with analysis of mechanisms involved in coordination of DNA replication and repair by SSB proteins; characteristics of eukaryotic, prokaryotic, and archaeal SSB proteins are considered, which made it possible to distinguish general mechanisms specific for functioning of proteins from organisms of different life domains. Mechanisms of SSB protein interactions with DNA during metabolism of the latter are studied; structural organization of the SSB protein complexes with DNA, as well as structural and functional peculiarities of different SSB proteins are analyzed.
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页码：1388 / 1404
页数：16
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