The importance of beta cell characterisation: generating human beta cells by differentiating human embryonic stem cells

被引:0
作者
G. S. Korbutt
T. Y. Yeung
C. E. Ellis
机构
[1] Alberta Diabetes Institute,Department of Surgery
[2] University of Alberta,5
来源
Diabetologia | 2012年 / 55卷
关键词
Beta cells; Embryonic stem cells;
D O I
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中图分类号
学科分类号
摘要
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页码:279 / 281
页数:2
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[1]  
Shapiro AM(1993)The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin dependent diabetes mellitus N Engl J Med 329 977-986
[2]  
Lakey JR(2000)Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen N Engl J Med 343 230-238
[3]  
Ryan EA(2007)Generation of insulin-producing islet-like clusters from human embryonic stem cells Stem Cells 25 1940-1953
[4]  
Jiang J(2008)In vivo characterization of transplanted human embryonic stem cell-derived pancreatic endocrine islet cells Cell Prolif 41 843-858
[5]  
Au M(2006)Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells Nat Biotechnol 24 1392-1401
[6]  
Lu K(2008)Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo Nat Biotechnol 26 443-542
[7]  
Eshpeter A(2010)Inconsistent formation and nonfunction of insulin-positive cells from pancreatic endoderm derived from human embryonic stem cells in athymic nude rats Am J Physiol Endocrinol Metab 299 E713-E720
[8]  
Jiang J(2011)Stage-specific signaling through TGFβ family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells Development 138 861-871
[9]  
Au M(1999)Cellular origin of hexokinase in pancreatic islets J Biol Chem 274 32803-32809
[10]  
D’Amour KA(2007)Physical exercise-induced hypoglycemia caused by failed silencing of monocarboxylate transporter 1 in pancreatic beta cells Am J Human Genet 81 467-474