Simultaneous Determination of Melamine and Clenbuterol in Animal Feeds by GC–MS

被引：2
|
作者：
Li Zhao
Jian Zhao
Wei-Guo Huangfu
Yin-Liang Wu
机构：
[1] Shanghai Agriculture Technical Extension Service Center,The Supervision, Inspection and Testing Center of Agricultural Products Quality and Security
[2] Ministry of Agriculture,undefined
[3] Ningbo,undefined
来源：
Chromatographia | 2010年 / 72卷
关键词：
Gas chromatography–mass spectrometry; Animal feedstuffs; Clenbuterol; Melamine;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A simple, sensitive and reliable GC–MS method for the simultaneous determination of clenbuterol and melamine in feeds was developed and validated. Samples were extracted with acetonitrile/50 mM HCl solution (1:1 v/v), then the extract was cleaned by extraction with ethyl acetate and solid phase extraction. The samples were derivatized with bis(trimethylsilyl)trifluoroacetamide. The selected ion mode detection method (197, 285, 327, 342 for melamine derivative, 86, 212, 262, 277 for clenbuterol derivative) was used. Recoveries of 70.8–92.0% were obtained. The detection limits were 0.6 µg kg−1 (melamine) and 2.40 µg kg−1 (clenbuterol) in feeds.
引用
收藏
页码：365 / 368
页数：3
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