Simvastatin plus irinotecan, 5-fluorouracil, and leucovorin (FOLFIRI) as first-line chemotherapy in metastatic colorectal patients: a multicenter phase II study

被引:0
|
作者
Jeeyun Lee
Kyung Hae Jung
Young Suk Park
Joong Bae Ahn
Sang Jun Shin
Seock-Ah Im
Do Youn Oh
Dong Bok Shin
Tae Won Kim
Namsu Lee
Jae Ho Byun
Yong Sang Hong
Joon Oh Park
Se Hoon Park
Ho Yeong Lim
Won Ki Kang
机构
[1] Sungkyunkwan University School of Medicine,Division of Hematology
[2] Research Institute and Hospital,Oncology, Department of Medicine, Samsung Medical Center
[3] Yonsei University College of Medicine,Center for Colorectal Cancer, National Cancer Center
[4] Seoul National University College of Medicine,Department of Internal Medicine
[5] Gachon University Gil Medical Center,Department of Internal Medicine
[6] University of Ulsan College of Medicine,Division of Hematology and Oncology, Department of Internal Medicine
[7] Soon Chun Hyang University Hospital,Division of Oncology, Department of Medicine, Asan Medical Center
[8] The Catholic University of Korea,Division of Hematology
来源
Cancer Chemotherapy and Pharmacology | 2009年 / 64卷
关键词
Statin; Simvastatin; Irinotecan; Cetuximab; Lovastatin;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:657 / 663
页数:6
相关论文
共 50 条
  • [21] A Phase II Study of Celecoxib With Irinotecan, 5-Fluorouracil, and Leucovorin in Patients With Previously Untreated Advanced or Metastatic Colorectal Cancer
    Chen, Emerson Y.
    Blanke, Charles D.
    Haller, Daniel G.
    Benson, Al B.
    Dragovich, Tomislav
    Lenz, Heinz-Josef
    Robles, Carlos
    Li, Hong
    Mori, Motomi
    Mattek, Nora
    Sanborn, Rachel E.
    Lopez, Charles D.
    AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS, 2018, 41 (12): : 1193 - 1198
  • [22] Phase II trial of irinotecan plus oxaliplatin and 5-fluorouracil/leucovorin in patients with untreated metastatic gastric adenocarcinoma
    Lee, J.
    Kang, W. K.
    Kwon, J. M.
    Oh, S. Y.
    Lee, H. R.
    Kim, H. J.
    Park, B. B.
    Lim, H. Y.
    Han, M. J.
    Park, J. O.
    Park, Y. S.
    ANNALS OF ONCOLOGY, 2007, 18 (01) : 88 - 92
  • [23] A phase II trial of gefitinib with 5-fluorouracil, leucovorin, and irinotecan in patients with colorectal cancer
    M L Veronese
    W Sun
    B Giantonio
    J Berlin
    J Shults
    L Davis
    D G Haller
    P J O'Dwyer
    British Journal of Cancer, 2005, 92 : 1846 - 1849
  • [24] A phase II trial of gefitinib with 5-fluorouracil, leucovorin, and irinotecan in patients with colorectal cancer
    Veronese, ML
    Sun, W
    Giantonio, B
    Berlin, J
    Shults, J
    Davis, L
    Haller, DG
    O'Dwyer, PJ
    BRITISH JOURNAL OF CANCER, 2005, 92 (10) : 1846 - 1849
  • [25] Phase II study of UFT with leucovorin and irinotecan (TEGAFIRI): first-line therapy for metastatic colorectal cancer
    J-P Delord
    J Bennouna
    P Artru
    H Perrier
    F Husseini
    F Desseigne
    E François
    R Faroux
    D Smith
    P Piedbois
    H Naman
    J Y Douillard
    R Bugat
    British Journal of Cancer, 2007, 97 : 297 - 301
  • [26] Phase II study of UFT with leucovorin and irinotecan (TEGAFIRI):: first-line therapy for metastatic colorectal cancer
    Delord, J-P
    Bennouna, J.
    Artru, P.
    Perrier, H.
    Husseini, F.
    Desseigne, F.
    Francois, E.
    Faroux, R.
    Smith, D.
    Piedbois, P.
    Naman, H.
    Douillard, J. Y.
    Bugat, R.
    BRITISH JOURNAL OF CANCER, 2007, 97 (03) : 297 - 301
  • [27] A Single Arm, Phase II Study of Simvastatin Plus XELOX and Bevacizumab as First-Line Chemotherapy in Metastatic Colorectal Cancer Patients
    Kim, Youjin
    Kim, Tae Won
    Han, Sae Won
    Ahn, Joong Bae
    Kim, Seung Tae
    Lee, Jeeyun
    Park, Joon Oh
    Park, Young Suk
    Lim, Ho Yeong
    Kang, Won Ki
    CANCER RESEARCH AND TREATMENT, 2019, 51 (03): : 1128 - 1134
  • [28] A Phase II Study of Irinotecan With Biweekly, Low Dose Leucovorin and Bolus and Continuous Infusion 5-Fluorouracil (Modified FOLFIRI) as First Line Therapy For Patients With Recurrent or Metastatic Gastric Cancer
    Kim, Byung Geun
    Oh, Sung Yong
    Kwon, Hyuk-Chan
    Lee, Suee
    Lee, Dong Mee
    Kim, Seong-Geun
    Kim, Do-Kyong
    Jang, Jin Seok
    Kim, Min Chan
    Kim, Sung-Hyun
    Kim, Hyo-Jin
    AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS, 2010, 33 (03): : 246 - 250
  • [29] Cetuximab plus oxaliplatin/leucovorin/5-fluorouracil in first-line metastatic gastric cancer: a phase II study of the Arbeitsgemeinschaft Internistische Onkologie (AIO)
    Lordick, F.
    Luber, B.
    Lorenzen, S.
    Hegewisch-Becker, S.
    Folprecht, G.
    Woell, E.
    Decker, T.
    Endlicher, E.
    Roethling, N.
    Schuster, T.
    Keller, G.
    Fend, F.
    Peschel, C.
    BRITISH JOURNAL OF CANCER, 2010, 102 (03) : 500 - 505
  • [30] A Randomized phase II trial of pemetrexed plus irinotecan (ALIRI) versus leucovorin-modulated 5-FU plus irinotecan (FOLFIRI) in first-line treatment of locally advanced or metastatic colorectal cancer
    Underhill, Craig
    Goldstein, David
    Gorbounova, Vera A.
    Biakhov, Mikhail Y.
    Bazin, Igor S.
    Granov, Dmitry A.
    Hossain, Anwar M.
    Blatter, Johannes
    Kaiser, Christopher
    Ma, Doreen
    ONCOLOGY, 2007, 73 (1-2) : 9 - 20