Sending out an SOS

被引：0

作者：

Kevin Shannon

Gideon Bollag

机构：

[1] University of California at San Francisco,Department of Pediatrics and Comprehensive Cancer Center

[2] Plexxikon,undefined

[3] Inc.,undefined

来源：

Nature Genetics | 2007年 / 39卷

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暂无

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摘要：

Noonan syndrome is a disease caused by aberrant signaling through the Ras GTPase, yet the underlying causal mutations remain unknown in many affected individuals. Two papers now identify gain-of-function mutations in the Ras nucleotide exchange factor SOS1 as a new player in this common developmental disorder.

引用

页码：8 / 9

页数：1