Sending out an SOS

被引：0
作者：
Kevin Shannon
Gideon Bollag
机构：
[1] University of California at San Francisco,Department of Pediatrics and Comprehensive Cancer Center
[2] Plexxikon,undefined
[3] Inc.,undefined
来源：
Nature Genetics | 2007年 / 39卷
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D O I：
暂无
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学科分类号：
摘要：
Noonan syndrome is a disease caused by aberrant signaling through the Ras GTPase, yet the underlying causal mutations remain unknown in many affected individuals. Two papers now identify gain-of-function mutations in the Ras nucleotide exchange factor SOS1 as a new player in this common developmental disorder.
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页码：8 / 9
页数：1
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