Selective Serotonin Reuptake Inhibitors for Late-Life DepressionA Comparative Review

被引：0
作者：
LalithKumar K. Solai
Benoit H. Mulsant
Bruce G. Pollock
机构：
[1] University of Pittsburgh School of Medicine,VA Pittsburgh Healthcare System
[2] University of Pittsburgh School of Medicine and Geriatric Research,Psychopharmacology and Pharmaceutical Sciences
[3] Education,Western Psychiatric Institute and Clinic
[4] and Clinical Center,undefined
[5] University of Pittsburgh School of Medicine and Geriatric Psychopharmacology Program,undefined
[6] University of Pittsburgh Medical Center,undefined
[7] UPMC Beaver Valley Mental Health Services,undefined
来源：
Drugs & Aging | 2001年 / 18卷
关键词：
Fluoxetine; Paroxetine; Sertraline; Fluvoxamine; Cisapride;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Late-life depression is a serious health problem that is challenging to manage but generally responds well to pharmacotherapy. Selective serotonin (5-hydroxy-tryptamine; 5-HT) reuptake inhibitors (SSRIs), the most commonly prescribed antidepressants, are usually used as first-line agents for elderly patients with depression. Like most drugs, SSRIs have not been widely tested in clinical trials that approximate ‘real-life’ geriatric situations. However, studies completed to date provide valuable information about the efficacy, safety and tolerability of this class of antidepressants among older patients with depression, including those with depression secondary to stroke or dementia and those with other comorbid physical disorders.
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页码：355 / 368
页数：13
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