Modulation of hippocampal protein expression by a brain penetrant biologic TNF-α inhibitor in the 3xTg Alzheimer’s disease mice

[1] Bloom GS(2014)Amyloid-β and tau: the trigger and bullet in Alzheimer disease pathogenesis JAMA Neurol 71 505-508

[2] Long JM(2019)Alzheimer disease: an update on pathobiology and treatment strategies Cell 179 312-339

[3] Holtzman DM(2023)The amyloid cascade hypothesis: an updated critical review Brain 146 3969-3990

[4] Kepp KP(2023)Towards a future where Alzheimer's disease pathology is stopped before the onset of dementia Nat Aging 3 494-505

[5] Robakis NK(2021)Beta amyloid, tau protein, and neuroinflammation: an attempt to integrate different hypotheses of Alzheimer’s disease pathogenesis Mol Biol (Mosk) 55 734-747

[6] Høilund-Carlsen PF(2021)Neuroinflammation and microglial activation in Alzheimer disease: where do we go from here? Nat Rev Neurol 17 157-172

[7] Sensi SL(2013)The amyloid cascade-inflammatory hypothesis of Alzheimer disease: implications for therapy Acta Neuropathol 126 479-497

[8] Vissel B(2020)The relationships between neuroinflammation, beta-amyloid and tau deposition in Alzheimer’s disease: a longitudinal PET study J Neuroinflammation 17 151-39

[9] van der Flier WM(2008)Neuroinflammation and tumor necrosis factor signaling in the pathophysiology of Alzheimer’s disease J Inflamm Res 1 29-59

[10] de Vugt ME(2012)Tumor necrosis factor-alpha and the roles it plays in homeostatic and degenerative processes within the central nervous system J Neuroimmune Pharmacol 7 42-318

[1] Bloom GS(2014)Amyloid-β and tau: the trigger and bullet in Alzheimer disease pathogenesis JAMA Neurol 71 505-508

[2] Long JM(2019)Alzheimer disease: an update on pathobiology and treatment strategies Cell 179 312-339

[3] Holtzman DM(2023)The amyloid cascade hypothesis: an updated critical review Brain 146 3969-3990

[4] Kepp KP(2023)Towards a future where Alzheimer's disease pathology is stopped before the onset of dementia Nat Aging 3 494-505

[5] Robakis NK(2021)Beta amyloid, tau protein, and neuroinflammation: an attempt to integrate different hypotheses of Alzheimer’s disease pathogenesis Mol Biol (Mosk) 55 734-747

[6] Høilund-Carlsen PF(2021)Neuroinflammation and microglial activation in Alzheimer disease: where do we go from here? Nat Rev Neurol 17 157-172

[7] Sensi SL(2013)The amyloid cascade-inflammatory hypothesis of Alzheimer disease: implications for therapy Acta Neuropathol 126 479-497

[8] Vissel B(2020)The relationships between neuroinflammation, beta-amyloid and tau deposition in Alzheimer’s disease: a longitudinal PET study J Neuroinflammation 17 151-39

[9] van der Flier WM(2008)Neuroinflammation and tumor necrosis factor signaling in the pathophysiology of Alzheimer’s disease J Inflamm Res 1 29-59

[10] de Vugt ME(2012)Tumor necrosis factor-alpha and the roles it plays in homeostatic and degenerative processes within the central nervous system J Neuroimmune Pharmacol 7 42-318