Brugada syndrome

被引:2
作者
Veltmann C. [1 ]
Oswald H. [1 ]
Bauersachs J. [1 ]
机构
[1] Klinik Fur Kardiologie und Angiologie, Medizinische Hochschule Hannover, 30625 Hannover
关键词
12-channel ECG; Brugada syndrome; Sudden cardiac death; Syncope; Syncope programmed stimulation;
D O I
10.1007/s00399-012-0231-9
中图分类号
学科分类号
摘要
Brugada syndrome is a rare, hereditary and primary electrical disease which is associated with a risk of syncope and sudden cardiac death. Initially, Brugada syndrome was considered to be a very malignant disease; however, in subsequent studies the risk of sudden death especially in asymptomatic patients was much lower than initially expected. In patients with Brugada type 1 electrocardiogram (ECG) findings and rhythmogenic syncope or sudden cardiac arrest, implantable cardioverter-defibrillator (ICD) implantation is indicated. Risk stratification and therapy in asymptomatic patients is controversially discussed and is clinically challenging. Due to the low event rate in asymptomatic patients with Brugada syndrome the identification of predictors of sudden cardiac death is difficult. Thus, risk stratification and therapy in asymptomatic patients has to be performed individually. This manuscript reviews the current data on diagnosis, risk stratification and therapy of Brugada syndrome. © Springer-Verlag 2012.
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页码:225 / 230
页数:5
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