A polygenic risk score for breast cancer risk in a Taiwanese population

被引：0

作者：

Yi-Chen Hsieh

Shih-Hsin Tu

Chien-Tien Su

Er-Chieh Cho

Chih-Hsiung Wu

Mao-Chih Hsieh

Shiyng-Yu Lin

Yun-Ru Liu

Chin-Sheng Hung

Hung-Yi Chiou

机构：

[1] Taipei Medical University,Graduate Institute of Neural Regenerative Medicine, College of Medical Science and Technology

[2] Taipei Medical University,Department of Surgery, School of Medicine, College of Medicine

[3] Taipei Medical University,Taipei Cancer Center

[4] Taipei Medical University Hospital,Breast Medical Center

[5] Taipei Medical University,School of Public Health, College of Public Health and Nutrition

[6] Taipei Medical University,Department of Family Medicine, School of Medicine, College of Medicine

[7] Taipei Medical University,Department of Clinical Pharmacy, School of Pharmacy, College of Pharmacy

[8] Taipei Medical University-Shuang Ho Hospital,Department of Surgery

[9] Taipei Medical University-Wan Fang Hospital,Department of Surgery

[10] Taipei Medical University,Joint Biobank, Office of Human Research

[11] Taipei Medical University,School of Public Health, College of Public Health and Nutrition

来源：

Breast Cancer Research and Treatment | 2017年 / 163卷

关键词：

Breast cancer; Polygenic risk score; Common variants; Risk prediction;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

页码：131 / 138

页数：7

共 120 条

[1] Moller S(2016)The heritability of breast cancer among women in the nordic twin study of cancer Cancer Epidemiol Biomark Prev 25 145-150
[2] Mucci LA(2011)Genome-wide association study identifies breast cancer risk variant at 10q21.2: results from the Asia Breast Cancer Consortium Hum Mol Genet 20 4991-4999
[3] Harris JR(2007)Genome-wide association study identifies novel breast cancer susceptibility loci Nature 447 1087-1093
[4] Cai Q(2008)Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33 Proc Natl Acad Sci USA 105 4340-4345
[5] Long J(2007)A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer Nat Genet 39 870-874
[6] Lu W(2012)A genome-wide association study identifies a breast cancer risk variant in ERBB4 at 2q34: results from the Seoul Breast Cancer Study Breast Cancer Res 14 R56-869
[7] Easton DF(2012)Genome-wide association study in East Asians identifies novel susceptibility loci for breast cancer PLoS Genet 8 e1002532-706
[8] Pooley KA(2007)Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor-positive breast cancer Nat Genet 39 865-191
[9] Dunning AM(2008)Common variants on chromosome 5p12 confer susceptibility to estrogen receptor-positive breast cancer Nat Genet 40 703-949
[10] Gold B(2010)Genetic susceptibility to breast cancer Mol Oncol 4 174-860