Biochemical Markers of Bone Metabolism in Breast Cancer

被引：0
作者：
N. V. Lyubimova
G. V. Kozharskaya
S. M. Portnoi
N. E. Kushlinskii
机构：
[1] the Russian Academy of Medical Sciences,N. N. Blokhin Russian Cancer Research Center
来源：
Bulletin of Experimental Biology and Medicine | 2014年 / 157卷
关键词：
biochemical markers; bone metastases; breast cancer;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The relationship between biochemical markers of bone resorption (C-terminal telopeptide, deoxypyridinoline, tartrate-resistant acid phosphatase 5b) and osteosynthesis (bone alkaline phosphatase) and clinical manifestations of bone metastases were studied in 239 patients with breast cancer with and without signs of bone involvement. High levels of C-terminal telopeptide and bone alkaline phosphatase were associated with poor prognosis: more severe skeletal complications and lesser survival values. These biochemical markers can be used for prognosis and optimization of therapy for bone metastases in patients with breast cancer.
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页码：769 / 772
页数：3
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