Cryospray ablation (CSA) in the palliative treatment of squamous cell carcinoma of the esophagus

被引:25
作者
Cash B.D. [1 ]
Johnston L.R. [2 ]
Johnston M.H. [2 ]
机构
[1] Department of Gastroenterology, National Naval Medical Center, Bethesda, MD 20889, Wisconsin Avenue
[2] Lancaster Gastroenterology, Inc., Lancaster, PA 17604-3200
关键词
Esophageal Cancer; Lansoprazole; Esophageal Carcinoma; African American Male; Sustained Remission;
D O I
10.1186/1477-7819-5-34
中图分类号
学科分类号
摘要
Background: Esophageal carcinoma is the ninth most prevalent cancer worldwide with squamous cell carcinoma (SCCA) and adenocarcinoma accounting for the vast majority of new cases (13,900 in 2003). Cure rates in the U.S. are less than 10%, similar to lung cancer. More than 50% of patients with esophageal carcinoma present with unresectable or metastatic disease, are not surgical candidates, or display disease progression despite the addition of neoadjuvant chemoradiotherapy to surgery. Need for improved palliation exits. Case presentation: This case describes a 73-year-old African American male who presented with recurrent squamous cell carcinoma (SCCA) of the esophagus who has a achieved complete remission for 24 months via endoscopic cryospray ablation. Conclusion: Endoscopic cryo spray ablation warrants further investigation as a palliative treatment modality for esophageal cancer. This is the first reported case in the medical literature. © 2007 Cash et al; licensee BioMed Central Ltd.
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