Microsatellite instability (MSI-H) is associated with a high immunoscore but not with PD-L1 expression or increased survival in patients (pts.) with metastatic colorectal cancer (mCRC) treated with oxaliplatin (ox) and fluoropyrimidine (FP) with and without bevacizumab (bev): a pooled analysis of the AIO KRK 0207 and RO91 trials

被引:0
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作者
Stefanie Noepel-Duennebacke
Hendrik Juette
Karsten Schulmann
Ulrich Graeven
Rainer Porschen
Jan Stoehlmacher
Susanna Hegewisch-Becker
Arne Raulf
Dirk Arnold
Anke Reinacher-Schick
Aandrea Tannapfel
机构
[1] St. Josef-Hospital,Department for Hematology, Oncology und Palliative Care
[2] Ruhr-University,Institute of Pathology
[3] Ruhr-University Bochum,Department for Hematology and Oncology
[4] Klinikum Hochsauerland,Department for Hematology, Oncology and Gastroenterology
[5] Kliniken Maria-Hilf Mönchengladbach,Medical Department
[6] Klinikum Bremen-Ost,Center for Protein Diagnostics, Bioinformatics Group, Faculty of Biology and Biotechnology
[7] Individuelle Krebsberatung,Asklepios Cancer Center, Department for Hematology, Oncology and Palliative Care
[8] HOPE—Practice for Oncology,undefined
[9] Ruhr-University,undefined
[10] Asklepios Klinikum Altona Hamburg,undefined
来源
Journal of Cancer Research and Clinical Oncology | 2021年 / 147卷
关键词
Metastatic colorectal cancer; Immunoscore; PD-L1; Microsatellite instability; Bevacizumab; Overall survival;
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页码:3063 / 3072
页数:9
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  • [1] Microsatellite instability (MSI-H) is associated with a high immunoscore but not with PD-L1 expression or increased survival in patients (pts.) with metastatic colorectal cancer (mCRC) treated with oxaliplatin (ox) and fluoropyrimidine (FP) with and without bevacizumab (bev): a pooled analysis of the AIO KRK 0207 and RO91 trials
    Noepel-Duennebacke, Stefanie
    Juette, Hendrik
    Schulmann, Karsten
    Graeven, Ulrich
    Porschen, Rainer
    Stoehlmacher, Jan
    Hegewisch-Becker, Susanna
    Raulf, Arne
    Arnold, Dirk
    Reinacher-Schick, Anke
    Tannapfel, Aandrea
    JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2021, 147 (10) : 3063 - 3072