Spinal cord repair: advances in biology and technology

被引:0
|
作者
Grégoire Courtine
Michael V. Sofroniew
机构
[1] Swiss Federal Institute of Technology (EPFL),Center for Neuroprosthetics and Brain Mind Institute, School of Life Sciences
[2] University Hospital Lausanne (CHUV),Department of Neurosurgery
[3] David Geffen School of Medicine,Department of Neurobiology
[4] University of California,undefined
[5] Los Angeles,undefined
来源
Nature Medicine | 2019年 / 25卷
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学科分类号
摘要
Individuals with spinal cord injury (SCI) can face decades with permanent disabilities. Advances in clinical management have decreased morbidity and improved outcomes, but no randomized clinical trial has demonstrated the efficacy of a repair strategy for improving recovery from SCI. Here, we summarize recent advances in biological and engineering strategies to augment neuroplasticity and/or functional recovery in animal models of SCI that are pushing toward clinical translation.
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页码:898 / 908
页数:10
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