Recent progress in West Nile virus diagnosis and vaccination

被引：0
作者：
Marina De Filette
Sebastian Ulbert
Michael S Diamond
Niek N Sanders
机构：
[1] Ghent University,Laboratory of Gene Therapy, Faculty of Veterinary Sciences
[2] Fraunhofer Institute for Cell Therapy and Immunology,Vaccine Technologies Unit
[3] Washington University School of Medicine,Departments of Medicine, Molecular Microbiology and Pathology & Immunology
来源：
Veterinary Research | / 43卷
关键词：
Surface Enhance Raman Scattering; West Nile Virus; Japanese Encephalitis Virus; Yellow Fever Virus; Plaque Reduction Neutralization Test;
D O I：
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摘要：
West Nile virus (WNV) is a positive-stranded RNA virus belonging to the Flaviviridae family, a large family with 3 main genera (flavivirus, hepacivirus and pestivirus). Among these viruses, there are several globally relevant human pathogens including the mosquito-borne dengue virus (DENV), yellow fever virus (YFV), Japanese encephalitis virus (JEV) and West Nile virus (WNV), as well as tick-borne viruses such as tick-borne encephalitis virus (TBEV). Since the mid-1990s, outbreaks of WN fever and encephalitis have occurred throughout the world and WNV is now endemic in Africa, Asia, Australia, the Middle East, Europe and the Unites States. This review describes the molecular virology, epidemiology, pathogenesis, and highlights recent progress regarding diagnosis and vaccination against WNV infections.
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