Major flares in women with SLE on combined oral contraception

被引：0
作者：
D. A. Whitelaw
S. J. Jessop
机构：
[1] Tygerberg Hospital,Division of Rheumatology
[2] Groote Schuur Hospital,Division of Dermatology
来源：
Clinical Rheumatology | 2007年 / 26卷
关键词：
Flares; Oral contraceptives; Systemic lupus erythematosus;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Two recent trials concluded that the use of oral contraceptives (OC) did not induce flares in lupus patients. We record our experience with OC in patients with stable lupus. Eight patients were enrolled in an open trial. Six received a combined contraceptive pill and two were allocated to the control arm. During a 12 month follow-up, 3 patients in the active arm experienced 4 major flares. One patient died as a result of uncontrolled disease complicated by sepsis. At this point, we abandoned the trial. The 2 patients in the control arm experienced no disease exacerbation during the 7 months of observation. We would urge that patients who are placed on OC be closely monitored.
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页码：2163 / 2165
页数：2
相关论文
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