Rutin inhibits carfilzomib-induced oxidative stress and inflammation via the NOS-mediated NF-κB signaling pathway

被引:0
作者
Naif O. Al-Harbi
Faisal Imam
Mohammed M. Al-Harbi
Othman A. Al-Shabanah
Moureq Rashed Alotaibi
Homood M. As Sobeai
Muhammad Afzal
Imran Kazmi
Ammar Cherkess Al Rikabi
机构
[1] King Saud University,Department of Pharmacology and Toxicology, College of Pharmacy
[2] Al Jauf University,Department of Pharmacology and Toxicology, College of Pharmacy
[3] Glocal University,Department of Pharmacology and Toxicology, School of Pharmacy
[4] King Khalid University Hospital,Department of Pathology, College of Medicine
来源
Inflammopharmacology | 2019年 / 27卷
关键词
Rutin; Carfilzomib; Nephrotoxicity; NOS-2; NF-κB; Histopathology;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:817 / 827
页数:10
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  • [1] Abarikwu SO(2016)Selenium and rutin alone or in combination do not have stronger protective effects than their separate effects against cadmium-induced renal damage Pharm Biol. 54 896-904
  • [2] Adebayo OL(2016)Carfilzomib-induced cardiotoxicity mitigated by dexrazoxane through inhibition of hypertrophic gene expression and oxidative stress in rats Toxicol Mech Methods 26 189-195
  • [3] Otuechere CA(2014)Olmesartan attenuates tacrolimus-induced biochemical and ultrastructural changes in rat kidney tissue Biomed Res Int 2014 1-7
  • [4] Iserhienrhien BO(2016)Dexamethasone attenuates LPS-induced acute lung injury through inhibition of Nf-κb, Cox-2, and pro-inflammatory mediators Immunol Invest 45 349-369
  • [5] Badejo TA(2014)Citrus, rutin and on their vein permeability effects RJAEM 3 80-81
  • [6] Al-Harbi NO(2013)Carfilzomib in multiple myeloma patients with renal impairment: pharmacokinetics and safety Leukemia 27 1707-1714
  • [7] Al-Harbi NO(2008)Update on uses and properties of citrus flavonoids: new findings in anticancer, cardiovascular, and antiinflammatory activity J Agric Food Chem 56 6185-6205
  • [8] Imam F(1985)Glutathione reductase Methods Enzymol 113 484-490
  • [9] Al-Harbi MM(2002)A role for superoxide in gentamicin-mediated nephropathy in rats Eur J Pharmacol 450 67-76
  • [10] Iqbal M(2007)Antitumor activity of PR171, a novel irreversible inhibitor of the proteasome Cancer Res 67 6383-6391