Lanthanum Potentiates GABA-Activated Currents in Rat Pyramidal Neurons of CA1 Hippocampal Field

被引:0
|
作者
A. A. Boldyreva
机构
[1] Russian Academy of Medical Sciences,Brain Research Institute
来源
Bulletin of Experimental Biology and Medicine | 2005年 / 140卷
关键词
GABA; pyramidal neurons; lanthanum; patch clamp;
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学科分类号
摘要
In CA1 hippocampal pyramidal neurons, lanthanum ions increased the amplitude of GABA-activated currents and shifted the dose-dependence curve to the left, which attests to increased affinity of GABAA-receptors to GABA. The data made it possible to compare the sensitivity GABAA-receptors of pyramidal neurons and similar receptors of other cells to GABA and lanthanum.
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页码:403 / 405
页数:2
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