Papaverine, a Phosphodiesterase 10A Inhibitor, Ameliorates Quinolinic Acid-Induced Synaptotoxicity in Human Cortical Neurons

[1] Abraham WC(2019)Is plasticity of synapses the mechanism of long-term memory storage? Npj Sci Learn 4 1-10

[2] Jones OD(2008)A time course of contusion-induced oxidative stress and synaptic proteins in cortex in a rat model of TBI J Neurotrauma 25 513-526

[3] Glanzman DL(2008)Oxidative stress and modification of synaptic proteins in hippocampus after traumatic brain injury Free Radic Biol Med 45 443-452

[4] Ansari MA(2017)Therapeutic targeting of the pathological triad of extrasynaptic NMDA receptor signaling in neurodegenerations J Exp Med 214 569-578

[5] Roberts KN(2018)Papaverine and its derivatives radiosensitize solid tumors by inhibiting mitochondrial metabolism Proc Natl Acad Sci U S A 115 10756-10761

[6] Scheff SW(2012)Oxidative stress and antioxidant defense World Allergy Organ J 5 9-19

[7] Ansari MA(2006)Phosphodiesterase inhibitors Br J Pharmacol 147 S252-S257

[8] Roberts KN(2009)Mechanism for quinolinic acid cytotoxicity in human astrocytes and neurons Neurotox Res 16 77-86

[9] Scheff SW(2010)Neuroprotective effects of naturally occurring polyphenols on quinolinic acid-induced excitotoxicity in human neurons FEBS J 277 368-382

[10] Bading H(2011)ROS-Ca2+ is associated with mitochondria permeability transition pore involved in surfactin-induced MCF-7 cells apoptosis Chem Biol Interact 190 16-27

[1] Abraham WC(2019)Is plasticity of synapses the mechanism of long-term memory storage? Npj Sci Learn 4 1-10

[2] Jones OD(2008)A time course of contusion-induced oxidative stress and synaptic proteins in cortex in a rat model of TBI J Neurotrauma 25 513-526

[3] Glanzman DL(2008)Oxidative stress and modification of synaptic proteins in hippocampus after traumatic brain injury Free Radic Biol Med 45 443-452

[4] Ansari MA(2017)Therapeutic targeting of the pathological triad of extrasynaptic NMDA receptor signaling in neurodegenerations J Exp Med 214 569-578

[5] Roberts KN(2018)Papaverine and its derivatives radiosensitize solid tumors by inhibiting mitochondrial metabolism Proc Natl Acad Sci U S A 115 10756-10761

[6] Scheff SW(2012)Oxidative stress and antioxidant defense World Allergy Organ J 5 9-19

[7] Ansari MA(2006)Phosphodiesterase inhibitors Br J Pharmacol 147 S252-S257

[8] Roberts KN(2009)Mechanism for quinolinic acid cytotoxicity in human astrocytes and neurons Neurotox Res 16 77-86

[9] Scheff SW(2010)Neuroprotective effects of naturally occurring polyphenols on quinolinic acid-induced excitotoxicity in human neurons FEBS J 277 368-382

[10] Bading H(2011)ROS-Ca2+ is associated with mitochondria permeability transition pore involved in surfactin-induced MCF-7 cells apoptosis Chem Biol Interact 190 16-27