Erythema multiforme and Stevens-Johnson syndrome following radiotherapy

被引:7
作者
Yoshitake T. [1 ]
Nakamura K. [1 ]
Shioyama Y. [1 ]
Sasaki T. [1 ]
Ooga S. [1 ]
Abe M. [1 ]
Urashima Y. [1 ]
Urabe K. [2 ]
Terashima H. [1 ]
Honda H. [1 ]
机构
[1] Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Higashi-ku, Fukuoka 812-8582
[2] Department of Dermatology, Graduate School of Medical Sciences, Kyushu University, Fukuoka
来源
Radiation Medicine | 2007年 / 25卷 / 1期
关键词
Erythema multiforme; Radiotherapy; Stevens-Johnson syndrome;
D O I
10.1007/s11604-006-0093-3
中图分类号
学科分类号
摘要
Erythema multiforme (EM) and Stevens-Johnson syndrome (SJS) are thought to be hypersensitivity syndromes with various causes, and radiotherapy might be one of the causes of these syndromes. We herein report two cases of EM/SJS following radiotherapy. The first case was a 63-year-old woman with breast cancer. At the end of postoperative radiotherapy with 60Gy, severe pruritic erythema appeared in the irradiated area and spread over the whole body. She was diagnosed with EM by a skin biopsy. The second case was a 77-year-old woman with uterine cervical cancer who underwent postoperative radiotherapy. At a dose of 30.6Gy, pruritic redness appeared in the irradiated area and the precordial region, and it became widespread rapidly with polymorphic transformation. Although without any histological confirmation, SJS was strongly suspected because of her pruritic conjunctivitis. Because both patients were given medicines during irradiation, radiotherapy may not be the only cause of EM/SJS. However, it should be noted that radiotherapy might trigger EM/SJS. © Japan Radiological Society 2007.
引用
收藏
页码:27 / 30
页数:3
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