Simultaneous LC Analysis of Aloe-Emodin, Rhein, Emodin, and Chrysophanol in Rhizoma Rhei-Type Preparations

被引：0
|
作者：
Ping Ren
Feng Qin
Xi Huang
Zhengyan Zhu
机构：
[1] Central South University,Laboratory of Ethnopharmacology, Institute of Integrated Traditional Medicine and Western Medicine, Xiangya Hospital
[2] Central South University,Key Unit of Traditional Chinese Medicine Gan of SATCM, Xiangya Hospital
[3] Central South University,Key Unit of the 11th Five
[4] Sichuan University,year Plan of SATCM in Cerebrosis, Xiangya Hospital
来源：
Chromatographia | 2009年 / 70卷
关键词：
Column liquid chromatography; Traditional Chinese medicine; Rhizoma Rhei; Anthraquinones;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A simple and sensitive liquid chromatographic method has been established for simultaneous analysis of four compounds (aloe-emodin, rhein, emodin, and chrysophanol) in Rhizoma Rhei-type preparations. The compounds were separated in less than 20 min on a C18 column with 70:30 methanol–0.2% aqueous acetic acid as mobile phase at a flow rate of 1 mL min−1. The method was validated for specificity, accuracy, precision, and limits of detection. Good linear regression data (r2 > 0.9980) were obtained for all the calibration plots within the ranges tested. The method is an attractive alternative for evaluation of the quality of Rhizoma Rhei-type preparations.
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页码：1515 / 1517
页数：2
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