Discovering antibiotics from the global microbiome

被引:0
|
作者
Yick Chong Lam
Jason M. Crawford
机构
[1] Yale University,Department of Chemistry, Chemical Biology Institute
[2] Department of Microbial Pathogenesis at the Yale School of Medicine,undefined
来源
Nature Microbiology | 2018年 / 3卷
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摘要
Metagenomic sequencing, bioinformatic analysis and heterologous expression of an orphan biosynthetic gene cluster widely found in the environment led to the discovery and structural characterization of a novel group of calcium-dependent antibiotics hidden in plain sight.
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页码:392 / 393
页数:1
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