Discovering antibiotics from the global microbiome

被引:0
|
作者
Yick Chong Lam
Jason M. Crawford
机构
[1] Yale University,Department of Chemistry, Chemical Biology Institute
[2] Department of Microbial Pathogenesis at the Yale School of Medicine,undefined
来源
Nature Microbiology | 2018年 / 3卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
Metagenomic sequencing, bioinformatic analysis and heterologous expression of an orphan biosynthetic gene cluster widely found in the environment led to the discovery and structural characterization of a novel group of calcium-dependent antibiotics hidden in plain sight.
引用
收藏
页码:392 / 393
页数:1
相关论文
共 50 条
  • [21] Strategies for Discovering New Antibiotics from Bacteria in the Post-Genomic Era
    Jia-Wei Zhu
    Si-Jia Zhang
    Wen-Guang Wang
    Hui Jiang
    Current Microbiology, 2020, 77 : 3213 - 3223
  • [22] The future of antibiotics begins with discovering new combinations
    Zhu, Meilin
    Tse, Megan W.
    Weller, Juliane
    Chen, Julie
    Blainey, Paul C.
    ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 2021, 1496 (01) : 82 - 96
  • [23] Discovering Enzymes for Synthesis of Antibiotics Related to Kanosamine
    Prasertanan, Theerawat
    Palmer, David R. J.
    Sanders, David A. R.
    PROTEIN SCIENCE, 2018, 27 : 35 - 35
  • [24] How Antibiotics Affect The Human Gut Microbiome: Lessons From The Extreme
    Xavier, Joao
    FASEB JOURNAL, 2016, 30
  • [25] Discovering multiple types of DNA methylation from bacteria and microbiome using nanopore sequencing
    Tourancheau, Alan
    Mead, Edward A.
    Zhang, Xue-Song
    Fang, Gang
    NATURE METHODS, 2021, 18 (05) : 491 - +
  • [26] Discovering multiple types of DNA methylation from bacteria and microbiome using nanopore sequencing
    Alan Tourancheau
    Edward A. Mead
    Xue-Song Zhang
    Gang Fang
    Nature Methods, 2021, 18 : 491 - 498
  • [27] Microbiome, antibiotics and irritable bowel syndrome
    Ahmad, O. F.
    Akbar, A.
    BRITISH MEDICAL BULLETIN, 2016, 120 (01) : 91 - 99
  • [28] Antibiotics impact honeybee gut microbiome
    不详
    LAB ANIMAL, 2017, 46 (05) : 194 - 195
  • [29] Antibiotics and the microbiome in asthmatic patients.
    O'Carroll, O. M.
    McGowan, A.
    Shah, W.
    Gough, C.
    Burke, C.
    IRISH JOURNAL OF MEDICAL SCIENCE, 2019, 188 (SUPPL 10) : 289 - 289
  • [30] Targeted microbiome-sparing antibiotics
    Avis, Tim
    Wilson, Francis X.
    Khan, Nawaz
    Mason, Clive S.
    Powell, David J.
    DRUG DISCOVERY TODAY, 2021, 26 (09) : 2198 - 2203