Insulin-like growth factors are essential to prevent anoikis in oestrogen-responsive breast cancer cells: importance of the type I IGF receptor and PI3-kinase/Akt pathway

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作者
Brendan C. Luey
Felicity E. B. May
机构
[1] Faculty of Medical Sciences,Northern Institute for Cancer Research and Newcastle University Institute for Ageing, Department of Pathology
[2] University of Newcastle upon Tyne,undefined
来源
Molecular Cancer | / 15卷
关键词
Akt PKB; mitogen-activated protein kinase (MAPK); anoikis; insulin-like growth factor (IGF); type I IGF receptor; oestrogen-dependent breast cancer; apoptosis; integrin; metastases; focal adhesion kinase (FAK);
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