Membranoproliferative glomerulonephritis following allogeneic hematopoietic stem cell transplantation

被引：0
作者：
Ju Youn Kim
Min Young Lee
Biro Kim
Cheol Whee Park
Yoon Sik Chang
Sungjin Chung
机构：
[1] The Catholic University of Korea,Division of Nephrology, Department of Internal Medicine, Yeouido St. Mary’s Hospital
[2] The Catholic University of Korea,Division of Nephrology, Department of Internal Medicine, Seoul St. Mary’s Hospital
来源：
Clinical and Experimental Nephrology | 2010年 / 14卷
关键词：
Nephrotic syndrome; Membranoproliferative glomerulonephritis; Graft-versus-host disease; Hematopoietic stem cell transplantation;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Nephrotic syndrome after allogeneic hematopoietic stem cell transplantation has been increasingly described as a manifestation of chronic graft-versus-host disease (GVHD); however, GVHD-associated membranoproliferative glomerulonephritis is extremely rare. A 44-year-old man developed nephrotic syndrome 24 months after HSCT for acute lymphoblastic leukemia. The renal biopsy showed type I membranoproliferative glomerulonephritis. Salivary gland biopsy demonstrated mild lymphocytic infiltration, indicating chronic GVHD. Improvement of the proteinuria and recovery of renal function were achieved within 11 months of treatment with oral prednisolone and azathioprine.
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页码：630 / 632
页数：2
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