Combined large cell neuroendocrine carcinoma with giant cell carcinoma of the lungs: a case report

被引：0
作者：
Satoshi Hayashi
Masahiro Kitada
Kei Ishibashi
Yoshinari Matsuda
Naoyuki Miyokawa
机构：
[1] Asahikawa Medical University Hospital,Respiratory Center
[2] Asahikawa Medical University Hospital,Department of Pathology
来源：
World Journal of Surgical Oncology | / 11卷
关键词：
Combined large cell neuroendocrine carcinoma; Lung; Giant cell carcinoma;
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摘要：
Combined large cell neuroendocrine carcinoma of the lungs (combined LCNEC) with giant cell carcinoma is extremely rare. A 65-year-old man was found to have an abnormal shadow in his left lung field. Computed tomography revealed a solid, round mass measuring 2.8 × 2.2 cm that was located in the left S9. The patient underwent left lower lobectomy and mediastinal lymph node dissection. Histopathological examination revealed an LCNEC, combined with giant cell carcinoma. The patient received by S-1 (TS-1, an oral fluoropyrimidine) chemotherapy, and he has been disease-free for over 8 months. Combined LCNEC with giant cell carcinoma is an extremely rare tumor with high malignant potential, and thus, multidisciplinary therapy and close follow-up are advised.
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