Azimuth-invariant mueller-matrix differentiation of the optical anisotropy of biological tissues

被引：0
|
作者：
V. A. Ushenko
M. I. Sidor
Yu. F. Marchuk
N. V. Pashkovskaya
D. R. Andreichuk
机构：
[1] Chernovtsy National University,Department of Optics and Spectroscopy
[2] Chernovtsy National University,undefined
[3] Bukovina State Medical University,undefined
来源：
Optics and Spectroscopy | 2014年 / 117卷
关键词：
Biological Tissue; Histological Section; Optical Anisotropy; Quarter Wave Plate; Linear Dichroism;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A Mueller-matrix model is proposed for analysis of the optical anisotropy of protein networks of optically thin nondepolarizing layers of biological tissues with allowance for birefringence and dichroism. The model is used to construct algorithms for reconstruction of coordinate distributions of phase shifts and coefficient of linear dichroism. Objective criteria for differentiation of benign and malignant tissues of female genitals are formulated in the framework of the statistical analysis of such distributions. Approaches of evidence-based medicine are used to determine the working characteristics (sensitivity, specificity, and accuracy) of the Mueller-matrix method for the reconstruction of the parameters of optical anisotropy and show its efficiency in the differentiation of benign and malignant tumors.
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页码：152 / 157
页数：5
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