A novel synthesis of (E)-1-(2-hydroxyphenyl)-3-(1Н-indol-3-yl)- prop-2-en-1-ones from chromone-3-carboxylic acid and indoles

被引:0
作者
Mikhail Yu. Kornev
Vladimir S. Moshkin
Vyacheslav Ya. Sosnovskikh
机构
[1] Ural Federal University named after the First President of Russia B. N. Yeltsin,Institute of Natural Sciences
来源
Chemistry of Heterocyclic Compounds | 2015年 / 51卷
关键词
chromone-3-carboxylic acid; indolyl chalcones; indoles; Michael addition;
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摘要
[graphic not available: see fulltext] The reaction of chromone-3-carboxylic acid with indoles in boiling ethanol proceeds as a 1,4-nucleophilic addition with successive opening of the pyrone ring and decarboxylation to afford a series of previously unknown trans-indolyl chalcones in 27–60% yields.
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页码:858 / 860
页数:2
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